心电图P波增宽及P波双峰与隐匿性高血压患者早期心脏损伤的关系研究  

Relationship between P-wave Broadening,Bimodal P-wave in ECG and Early Cardiac Damage in Patients with Masked Hypertension

作　　者：彭城 祁春梅 冯建启 PENG Cheng;QI Chun-mei;FENG Jian-qi(Department of Cardiology,the Second Affiliated Hospital of Xuzhou Medical University(General Hospital of Xuzhou Mining Group),Xuzhou 221002,China)

机构地区：[1]徐州医科大学第二附属医院(徐州矿务集团总医院)心内科,江苏省徐州市221002

出　　处：《实用心脑肺血管病杂志》2018年第10期37-40,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探讨心电图P波增宽及P波双峰与隐匿性高血压(MH)患者早期心脏损伤的关系。方法选取2015年7月—2017年7月徐州医科大学第二附属医院心内科门诊及住院的92例MH患者作为MH组,96例真性高血压患者作为高血压组。比较两组患者早期心脏损伤发生率及P波增宽、P波双峰检出率,有无早期心脏损伤的MH患者一般资料及P波增宽、P波双峰检出率;P波增宽、P波双峰与MH患者早期心脏损伤的关系分析采用多因素Logistic回归分析。结果 (1)MH组患者早期心脏损伤发生率低于高血压组(P<0.05);两组患者P波增宽、P波双峰检出率比较,差异无统计学意义(P>0.05)。(2)有无早期心脏损伤的MH患者性别、年龄、体质指数(BMI)比较,差异无统计学意义(P>0.05);有无早期心脏损伤的MH患者高血压家族史、吸烟史、P波增宽及P波双峰检出率比较,差异有统计学意义(P<0.05)。(3)多因素Logistic回归分析结果显示,P波增宽[OR=2.793,95%CI(1.243,6.274)]、P波双峰[OR=3.074,95%CI(1.474,6.411)]是MH患者早期心脏损伤的独立危险因素(P<0.05)。结论 MH对心脏的早期损伤小于真性高血压;心电图P波增宽及P波双峰是MH患者早期心脏损伤的独立危险因素,应引起临床重视。Objective To relationship between P-wave broadening,bimodal P-wave in ECG and early cardiac damage in patients with masked hypertension.Methods From July2015to July2017,a total of92outpatients and in patients with masked hypertension were selected as A group in the Department of Cardiology,the Second Affiliated Hospital of Xuzhou Medical University,meanwhile a total of96patients with true hypertension were selected as B group.Incidence of early cardiac damage,detection rates of P-wave broadening and bimodal P-wave in ECG were compared between the two groups,meanwhile general information,detection rates of P-wave broadening and bimodal P-wave in ECG were compared in masked hypertension patients with early cardiac damage or not;multivariate Logistic regression analysis was used to analyze the relationship between P-wave broadening,bimodal P-wave in ECG and early cardiac damage in patients with masked hypertension.Results(1)Incidence of early cardiac damage in A group was statistically significantly lower than that in B group(P<0.05),while no statistically significant differences of detection rate of P-wave broadening or bimodal P-wave in ECG was found between the two groups(P>0.05).(2)No statistically significant differences of gender,age or BMI was found in masked hypertension patients with early cardiac damage or not(P>0.05),while there were statistically significant differences of familial history of hypertension,smoking history,detection rates of P-wave broadening and bimodal P-wave in ECG in masked hypertension patients with early cardiac damage or not(P<0.05).(3)Multivariate Logistic regression analysis results showed that,P-wave broadening〔OR=2.793,95%CI(1.243,6.274)〕and bimodal P-wave〔OR=3.074,95%CI(1.474,6.411)〕in ECG were independent risk factors of early cardiac damage in patients with masked hypertension(P<0.05).Conclusion Risk of early cardiac damage is relativity low than that in patients with true hypertension;P-wave broadening and bimodal P-wave in ECG were independent risk factors of early

关 键 词：隐匿性高血压 心电描计术 P波增宽 P波双峰 心脏损伤 

分 类 号：R544.1[医药卫生—心血管疾病]