获得性反应性穿通性胶原病九例临床及病理分析  

Clinical analyses of 9 cases with acquired reactive perforating collagenosis

作　　者：吕静[1] 肖沙[1] 赵鹏[1] 阎衡[1] 黄燕 郝进[1] 高涛[1] LV Jing;XIAO Sha;ZHAO Peng;YAN Heng;HUANG Yan;HAO Jin;GAO Tao(Department of Dermatology,the First People s Hospital,Traditional Chinese Medicine Hospital,Chongqing 400011,China)

机构地区：[1]重庆市第一人民医院(重庆市中医院),重庆400011

出　　处：《中国麻风皮肤病杂志》2018年第11期669-671,共3页China Journal of Leprosy and Skin Diseases

摘　　要：对2015年1月至2017年12月我院9例获得性反应性穿通性胶原病临床资料和组织病理进行回顾性分析。其中男女比例为1∶1.25,平均发病年龄53.89岁,平均病程9.67个月,临床皮损形态多样,组织病理均可见变性的胶原纤维穿出表皮,有8例患者(88.9%)伴有糖尿病,2例患者(25%)伴有高血压。9例患者均被误诊为其他疾病,最易误诊为结节性痒疹和湿疹或湿疹样皮炎,其余依次是皮肤血管炎、坏疽性脓皮病、皮肤溃疡、真菌感染、神经性皮炎、痒疹性大疱性类天疱疮、大疱性表皮松解症、扁平苔藓,均为1例次。Clinical and pathological data of 9 cases with acquired reactive perforating collagenosis from Jan.2015 to Dec.2017 were retrospectively analyzed.The ratio of male to female was 1∶1.25.The average age at onset was 53.89 years old.The average duration was 9.67 months.The biopsy shows denatured collagen fibers within the epidermis.There were 8 cases(88.9%)with diabetes,2(25%)with hypertension.All 9 patients were misdiagnosed as other diseases,including prurigo nodular,eczema,cutaneous vasculitis,pyoderma gangrenosum skin ulcers,mycotic infection,neurodermitis prurigo bullous pemphigoid,epidermolysis bullosa,lichen planus(1 time).

关 键 词：获得性反应性穿通性胶原病 临床 病理 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]