DL-蛋氨酸不同晶型在水中溶解度的研究  

Solubility of DL-methionine of Different Crystal Forms in Water

作　　者：练婉 杨立斌 沙作良 朱亮 王彦飞 赵晓昱 LIAN Wan;YANG Libin;SHA Zuoliang;ZHU Liang;WANG Yanfei;ZHAO Xiaoyu(Tianjin Marine Chemical Engineering Center,College of Chemical Engineering and Materials Science,Tianjin University of Science&Technology,Tianjin 300457,China)

机构地区：[1]天津市海洋化工工程中心,天津科技大学化工与材料学院,天津300457

出　　处：《天津科技大学学报》2018年第6期45-48,共4页Journal of Tianjin University of Science & Technology

摘　　要：用硫酸和氢氧化钠作为调节剂,并采用间接碘量法分析测量了不同温度、不同pH下α和γ型蛋氨酸(DLMet)固体在水中的溶解平衡数据,在分析其离子化溶解机理的基础上建立溶解平衡模型,描述预测其溶解特性.实验结果研究表明:离子化平衡模型可准确地描述蛋氨酸在水中溶解情况和离子化程度,即随pH的增大,两种晶型的DLMet在水中的溶解度先减小后增大,极值点为等电点;温度升高使得两种晶型的DL-Met在水中溶解增加,且溶解度差值缩小.Sulfuric acid and sodium hydroxide used as regulators,the solubility ofαandγ-methionine(DL-Met)in water under different temperatures and pH values was determined with the indirect iodometric method.A solubility equilibrium model was established to describe the solubility characteristics of DL-Met based on the analysis of the dissolution mechanism of DL-Met.The experimental results indicated that the ionization equilibrium model can accurately describe the solubility and ionization degree of methionine in water.With the increase of pH value,the solubility ofαandγDL-Met decreased first and then increased,and the minimum point was the isoelectric point.The increase of temperature makes the solubility ofαandγDL-Met increase in water,and the difference of solubility is narrowed.

关 键 词：DL–蛋氨酸 溶解平衡 模型 晶型 等电点 pH 间接碘量法 

分 类 号：O792[理学—晶体学] R9[医药卫生—药学]