白塞氏病导致主动脉瓣关闭不全的治疗  

Treatment of aortic regurgitation caused by Behcet′s disease

作　　者：杨宗达 封加涛[1] 简劲峰[1] 苏艳玲[1] 叶华安[1] 林家旺[1] 赵铎[1] YANG Zong-da;FENG Jia-tao;JIAN Jing-feng;SU Yan-ling;YE Hua-an;LIN Jia-wang;ZHAO Duo(Department of Cardiac Surgery,The First People′s Hospital of Foshan,Foshan,Guangdong 528000,China)

机构地区：[1]佛山市第一人民医院心血管外科,广东佛山528000

出　　处：《岭南心血管病杂志》2018年第6期683-687,共5页South China Journal of Cardiovascular Diseases

摘　　要：目的探讨白塞氏病所致主动脉瓣关闭不全的外科和药物治疗方式。方法回顾性分析2000年5月至2013年9月佛山市第一人民医院诊断的以心脏瓣膜病变为突出表现的白塞氏病患者6例的治疗和随访情况。结果 1例患者第1次、第2次手术都为常规主动脉瓣置换术,第3次手术为自体心包加固主动脉瓣环+Bentall手术,存活;其余5例患者第1次进行自体心包加固主动脉瓣环+Bentall手术,其中1例患者术后5个月出现了瓣周漏,心力衰竭死亡,其余4例患者存活。结论白塞氏病所致主动脉瓣关闭不全可以使用自体心包加固主动脉瓣环,然后进行Bentall手术,术前和术后使用强的松和沙利度胺控制炎症,效果良好。Objectives To discuss the choice of surgical method and medicine of aortic regurgitation caused by Behcet′s disease.Methods Treatment and follow-up data of6patients with aortic regurgitation secondary to Behcet′s disease and received surgery between May2000and September2013in The First People′s Hospital of Foshan were retrospectively analyzed.Results One patient undertook aortic valve replacement(AVR)in the first and second operation,and he received modified Bentall operation in the third operation and he finally survived;the rest patients undertook modi?fied Bentall operation in the first operation,one of the5patients had perivalvular leakage5months after operation and died from heart failure.Four patients received Bentall operation and survived.Conclusions Modified Bentall operation should be a first-line therapy for aortic regurgitation caused by Behcet′s disease.These patients should be administered prednisone and thalidomide to control the inflammation.

关 键 词：白塞氏病 主动脉瓣关闭不全 BENTALL手术 

分 类 号：R543.1[医药卫生—心血管疾病]