中药温肾健脾法治疗肠道菌群失调性腹泻的临床疗效  

Clinical Effects of the Warming Kidney and Vitalizing Spleen of Chinese Medicines in Treating Diarrhea of Intestinal Dysbacteriosis

作　　者：王世栋 蔡颖 单国辉[3] 杨东宇 Wang Shidong;Cai Ying;Shan Guohui;Yang Dongyu(Department of Intensive Medicine,Beihai Hospital of Traditional Chinese Medicine,Beihai 536000,China;Department of Pediatrics,Beihai Hospital of Traditional Chinese Medicine,Beihai 536000,China;Department of Endocrine,Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China;Department of Chinese Internal Medicinal,Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)

机构地区：[1]北海市中医医院重症医学科,北海536000 [2]北海市中医医院儿科,北海536000 [3]长春中医药大学附属医院内分泌科,长春130021 [4]长春中医药大学附属医院中医内科门诊,长春130021

出　　处：《世界中医药》2018年第12期3039-3042,共4页World Chinese Medicine

基　　金：国家自然科学基金项目(30971296)

摘　　要：目的:探讨中药温肾健脾法治疗肠道菌群失调性腹泻的临床疗效;方法:选取2016年4月至2017年9月北海市中医医院收治的肠道菌群失调性腹泻患者50例,采用随机数字表法分为观察组和对照组,每组25例,其中观察组采用中药温肾健脾法进行治疗,对照组采用双歧杆菌活菌胶囊进行治疗,比较分析2组患者的临床效果;结果:观察组的起效时间优于对照组,差异有统计学意义(P <0. 05);观察组总有效率(88. 00%)优于对照组总有效率(76. 00%),差异有统计学意义(P <0. 05);结论:中药温肾健脾法治疗肠道菌群失调性腹泻的临床疗效好于采用双歧杆菌活菌胶囊。To investigate the clinical effects of the warming kidney and vitalizing spleen of Chinese medicines in the treatment of intestinal flora with inactivation diarrhea Methods:A total of 50 cases of intestinal flora of tonal diarrhea were selected in our hospital from April 2016 to September 2017,and they were randomly divided into observation group and control group by random number table,with 25 cases in each group.The observation group used warming the kidney and vitalizing spleen of traditional Chinese medicine treatment,while the control group adopted the Bifidobacterium viable capsule treatment.The clinical effects of 2 groups were compared.Results:The effective time of observation group was earlier than that of the control group.The difference between 2 groups was statistically significant(P<0.05).The total effective rate of the observation group(88.00%)was better than that of the control group(76.00%),and the differences between the 2 groups were statistically significant(P<0.05).Conclusion:The clinical manifestations of this disease are different,with 1 symptom as the major and other symptoms.Therefore,the history of diarrhea is very long,and the dampness and heat pathogen of the patient should be taken into consider when taking the medicine.The patient′s symptoms need to be identified,and taking medicines based on pattern differentiation could achieve the best potential effects.Strengthening the study on the spleen and gut microbial ecology of traditional Chinese medicine will help confirm the symptoms of spleen deficiency leading to damp encumbrance.Probiotics play an important role in clarifying the etiology of intestinal disease.Meanwhile it has a key role on treatment strategies.

关 键 词：中药温肾健脾法 肠道菌群失调性腹泻 临床疗效 双歧杆菌活菌胶囊 西医 中医 益生菌 脾虚 

分 类 号：R242[医药卫生—中医临床基础]