中药内服治疗腰椎骨性关节炎近10年文献潜在用药规律探讨  

Discussion on Potential Rules about Lumbar Osteoarthritis with Traditional Chinese Medicine Therapy in Documents in Past 10 Years

作　　者：贾涛[1,2] 刘盾 赖福崇[1,2] 李文豪[1,2] 李骥征 韦佳佳 张伟强 李鹏飞 李具宝[1,2] Jia Tao;Liu Dun;Lai Fuchong;Li Wenhao;,Li Jizheng;Wei Jiajia;Zhang Weiqiang;Li Pengfei;Li Jubao(Yunnan Provincial Hospital of Traditional Chinese Medicine,Kunming 650021,China;;Yunnan University of Traditional Chinese Medicine,Kunming 650500,China)

机构地区：[1]云南省中医医院,昆明650021 [2]云南中医学院,昆明650500

出　　处：《世界中医药》2018年第12期3212-3218,共7页World Chinese Medicine

基　　金：国家自然科学基金地区基金项目(81460736)--模拟拔伸;按压;斜扳及其复合手法对各型腰突症三维有限元模型作用机制的研究;云南省科技计划面上项目(2016FB141);云南省医疗卫生单位内设研究机构科研项目(2016NS172;2016NS171;2016NS170)

摘　　要：目的:探讨治疗腰椎骨性关节炎的内服中药用药规律,为腰椎骨性关节炎临床中的辨证论治和遣方用药提供相应的理论依据。方法:检索近10年内服中药治疗腰椎骨性关节炎的临床文献,通过统一的纳入标准、排除标准,合并和删除重复文献,分析腰椎骨性关节炎的内服中药用药规律。结果:从693篇有效文献中总结出使用频率最多的前30味中药依次是:当归、川芎、甘草、杜仲、牛膝、熟地黄、白芍、独活、红花、茯苓、肉桂、秦艽、细辛、没药、黄芪、桑寄生、桃仁、地龙、防风、乳香、续断、党参、全蝎、鸡血藤、附子、威灵仙、赤芍、木瓜、山茱萸、丹参。结论:近10年文献中内服中药治疗腰椎骨性关节炎的功效主要以活血化瘀、补益肝肾、强筋健骨、祛风散寒除湿、补气养血为主。Objective:To discuss the rules of lumbar osteoarthritis with traditional Chinese medicine prescription.To provide some theoretical basis and document for clinical use on dialectical treatment and herbal prescription.Methods:Searching the clinical document of traditional Chinese medicine for treatment of lumbar osteoarthritis for 10 years,the rules of traditional Chinese medicine for oral administration in lumbar osteoarthritis were analyzed by the combination of inclusion criteria and exclusion criteria,and combined and deleted duplicate paper.Results:A total of 30 Chinese herbs summarized from 693 effective document most frequently used as follows:Radix Angelicae Sinensis,Rhizoma Ligustici Chuanxiong,Radix Glycyrrhizae,Cortex Eucommiae,Radix Achyranthis Bidentatae,Radix Rehmanniae Preparata,Radix Paeoniae Alba,Flos Carthami,Poria,etc.Conclusion:Nearly 10 years,the effects of herbs on treating lumbar osteoarthritis are based on upon promoting blood and dissolving stasis,nourishing liver and kidney,strengthening tendons and bones,expelling wind and cold,replenishing Qi and nourishing blood.

关 键 词：腰椎骨性关节炎 中医药 数据挖掘 文献研究 

分 类 号：R289.1[医药卫生—方剂学] R289.5[医药卫生—中药学]