腹腔镜胆囊切除术治疗老年结石性胆囊炎患者的临床效果  

Clinical effect of laparoscopic cholecystectomy in the treatment of elderly patients with calculous cholecystitis

作　　者：孙万亮 马翔[1] 张登勇 鲁正[1] 吴斌全[1] 吴华[1] 崔培元[1] SUN Wan-liang;MA Xiang;ZHANG Deng-yong;LU Zheng;WU Bin-quan;WU Hua;CUI Pei-yuan(Department of Hepatobiliary Surgery,the First Affiliated Hospital of Bengbu Medical College,Anhui Province,Bengbu233000,China)

机构地区：[1]蚌埠医学院第一附属医院肝胆外科,安徽蚌埠233000

出　　处：《中国当代医药》2018年第34期51-53,共3页China Modern Medicine

摘　　要：目的探讨和分析腹腔镜胆囊切除术治疗老年结石性胆囊炎患者的临床效果。方法选取本院2016年2月～2018年4月接收治疗的100例结石性胆囊炎患者,随机分为实验组和对照组,各50例。实验组患者应用腹腔镜胆囊切除术,对照组患者采用常规开腹胆囊切除术。观察两组不同治疗方法患者手术所需要的时间、留院观察需要的时间以及术中患者出血量之间的差异,比较两组患者的临床疗效。结果实验组患者手术时间、住院时间短于对照组(P<0.05),实验组患者的术中出血量少于对照组(P<0.05)。实验组的总有效率为94%,明显高于对照组的80%(P<0.05),实验组术后的炎症因子IL-6、IL-8、TNF-α水平明显低于对照组(P<0.05),实验组肠鸣音恢复时间、肛门恢复排气所需要的时间以及可以正常排便所需要的时间均明显早于对照组(P<0.05)。结论应用腹腔镜胆囊切除术治疗老年结石性胆囊炎疾病较常规开腹胆囊切除术临床效果更加明显,值得临床推广。Objective To explore the clinical effect of laparoscopic cholecystectomy in the treatment of elderly patients with calculous cholecystitis.Methods From February 2016 to April 2018,100 patients with calculous cholecystitis were selected and randomly divided into the experimental group and the control group,50 cases in each group.The patients in the experimental group were treated by laparoscopic cholecystectomy,the patients in the control group were treated by routine open cholecystectomy.The time required for operation,the time required to stay in hospital and the amount of blood lost during the operation were observed,and the clinical efficacy of the two groups was compared.Results The time required for operation,the time required to stay in hospital in the experimental group were shorter than those in the control group(P<0.05),and the amount of intraoperative bleeding in the experimental group was less than that in the control group(P<0.05).The total effective rate of the experimental group was 94%,which was higher than that of the control group(80%)(P<0.05).The inflammatory factor of IL-6,IL-8,TNF-αin the experimental group were lower than those in the control group(P<0.05).In the experimental group,the recovery time of the bowel and stomach sound,the time of the recovery of anal exhaust and the time of normal defecation were significantly earlier than those of the control group(P<0.05).Conclusion Laparoscopic cholecystectomy is more effective than conventional open cholecystectomy in the treatment of senile cholecystitis.It is worth popularizing.

关 键 词：结石性胆囊炎 腹腔镜胆囊切除术 开腹胆囊切除术 炎症因子 胃肠功能 

分 类 号：R657.42[医药卫生—外科学]