MRI对胎儿侧脑室扩张合并中枢神经系统病变诊断的临床应用  

Application of MRI in the diagnosis of fetal lateral ventriculomegaly with nervous system abnormalities

作　　者：陈芳芳 胡龙 刘影[1] 徐运军[1] CHEN Fang-fang;HU Long;LIU Ying;XU Yun-jun(Department of Radiology,the First Affiliated Hospital of China Science and Technology University,Hefei 230000,China)

机构地区：[1]中国科学技术大学附属第一医院/安徽省立医院,合肥230000

出　　处：《磁共振成像》2018年第12期881-885,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：安徽省自然科学基金面上项目(编号:1708085ME114)~~

摘　　要：目的探讨MRI对胎儿侧脑室扩张合并中枢神经系统病变诊断的临床应用。材料与方法抽取2015年1月1日至2018年3月1日在我院行胎儿颅脑磁共振检查后诊断为至少一侧侧脑室扩张的118例孕妇作为研究对象,根据侧脑室扩张程度分为轻、中、重度,A组为轻度(10.1～12.0 mm),B组为中度(12.1～15.0mm),C组为重度(>15.0mm),并根据双侧脑室扩张差异是否大于2mm,分为对称性及非对称性扩张,对其磁共振影像进行回顾性分析,并比较各组合并中枢系统病变的差异情况。结果 A、B、C 3组中非对称性侧脑室扩张数量均高于对称性侧脑室扩张。A、B、C 3组中合并中枢神经系统病变的比例分别为25%、21%及49%,A组与C组、B组与C组在合并中枢神经系统病变的比较差异有统计学意义(P<0.05)。对称性侧脑室扩张合并中枢神经系统病变的比例(39%)高于非对称组(21%),两者比较差异有统计学意义(P=0.034);并且A组与C组在对称性侧脑室扩张合并中枢神经系统病变的比较差异有统计学意义(P<0.05)。A组非对称脑室扩张组中另一侧侧脑室宽度均小于10.0mm。B组非对称脑室扩张组中另一侧侧脑室宽度在小于10.0 mm及10.1～12.0 mm范围内,两者合并中枢神经系统病变比例相仿,分别为18%、17%。C组中非对称脑室扩张组中另一侧侧脑室宽度在12.0～15.0 mm范围内合并中枢神经系统病变的比例较高(75%)。结论 MRI对胎儿侧脑室扩张合并中枢神经系统病变的诊断中有重要临床价值,重度对称性侧脑室扩张的胎儿合并中枢神经系统病变的发生率明显增高。Objective:To evaluate the application of MRI in the diagnosis of fetal lateral ventriculomegaly with nervous system abnormalities.Materials and Methods:A total of118pregnant women diagnosed with at least one lateral ventricle dilation after performing MRI examination in the First Affiliated Hospital of China Science and Technology University between January1,2015and March1,2018were included in the study,Acording to the degree of the ventriculomegaly,it can be devided into mild,moderate and severe,Group A:mild was10.0-12.0mm;Group B:moderate if,12.1-15.0mm,Group C:severe if,>15.0mm.Asymmetry was defined as a difference of>2mm between the2lateral ventricles.All of their magenetic resonance image were retrospectively analyzed,and comparison of the diference in the fetal nervous system abnormalities.Results:The number of asymmetric lateral ventriculomegaly in A,B,and C groups was higher than that in symmetric lateral ventriculomegaly.The proportion of the central nervous system lesions in the A,B,and C groups was25%,21%and49%,respectively.There was a statistically significant difference between group A and group C,group B and group C with the central nervous system abnormalities,P<0.05.The prevalence of associated central nervous system abnormalities was significantly higher(P=0.034)in symmetric ventriculomegaly compared with asymmetric ventriculomegaly(39%versus21%,respectively).In additional,there was a statistical significance between the group A and the group C in the symmetric lateral ventriculomegaly with nervous system abnormalities.The width of the other ventricle in the asymmetric lateral ventriculomegaly of group A was less than10.0mm.In group B,the width of the other ventricle in the asymmetric lateral ventuiculomegaly was less than10.0mm,and the proportion of central nervous abnormalities was18%.The width in the range of10.1-12.0mm,and the proportion of central nervous abnormalities was17%.In group C,the width of the other ventricle in the asymmetric lateral ventuiculomegaly in the range of12.1-15.0mm,and

关 键 词：侧脑室扩张 磁共振成像 胎儿 中枢神经系统疾病 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]