秦皇岛地区健康体检人群甲状腺功能情况调查  

The investigation of thyroid function among the checkup people in Qinhuangdao area

作　　者：佟瑞[1] 武文平[1] 李艳霞 TONG Rui;WU Wenping;LI Yanxia(Clinical laboratory,Qinhuangdao Traditional Chinese Medicine Hospital,Qinhuangdao City,Hebei Province,066000,China)

机构地区：[1]秦皇岛市中医医院检验科,河北066000

出　　处：《国际检验医学杂志》2018年第A02期67-70,共4页International Journal of Laboratory Medicine

摘　　要：目的调查分析秦皇岛地区健康体检人群的甲状腺功能异常情况。方法收集2017年8月至2018年3月来本院体检中心健康体检者540例,其中男272例,女268例子,按照不同年龄各自分成4组。所有人均进行游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)、三碘甲状腺原氨酸(T3)及甲状腺素(T4)检测,并对检测结果进行统计学分析。结果540例健康体检人群中,甲状腺功能异常者总体检出率为13.52%(73/540),女性检出率16.79%(45/268)高于男性10.29%(28/272),差异有统计学意义(P<0.05)。其中临床甲亢、亚临床甲亢、临床甲减、亚临床甲减的检出率分别为0.19%(1/540)、0.56%(3/540)、0.74%(4/540)、12.04%(65/540)。亚临床甲减的男女检出率分别为9.93%(27/272)、14.18%(38/268),差异无统计学意义(P>0.05),且高发年龄段均为40~49岁。结论秦皇岛地区健康体检人群中亚临床甲减的发病率较高,特别是40-49岁人群更应该提高警惕和重视。男性亚临床甲减的发病率也很高,应给予关注和重视。定期进行甲状腺功能筛查很必要。Objective To investigate and analyze the thyroid dysfunction among the checkup people in Qinhuangdao area.Methods A total of 540 cases of checkup adults were collected from August 2017 to March 2018 in the Health Check-up Department of our hospital,with 272 cases of male and 268 cases of female.They were divided into four groups on the basis of different ages.Free triiodothyronine(FT3),Free thyroxine(FT4),Thyroid Stimulating Hormone(TSH),triiodothyronine(T3)and thyroxine(T4)were detected in all the people with the results were analyzed by statistical methods.Results Of the 540 cases,the detection rate for thyroid dysfunction was 13.52%(73/540),with 16.79%(45/268)in female higher than that 10.29%(28/272)in male(P<0.05).The detection rate of clinical hyperthyroidism,subclinical hyperthyroidism,clinical hypothyroidism and subclinical hypothyroidism was 0.19%(1/540),0.56%(3/540),0.74%(4/540)and 12.04%(65/540)respectively.For male and female,the detection rate of subclinical hypothyroidism was 9.93%and 14.18%(P>0.05).Highly rate of subclinical hypothyroidism was found between 40 and 49 years old both in male and female.Conclusion There is a high incidence of subclinical hypothyroidism among the checkup people in Qinhuangdao area,especially for the persons between 40-49 years old,who shoud be pay more attention to the disease.The high incidence of subclinical hypothyroidism in male shoud be given more attention.Regular thyroid screening is essential.

关 键 词：甲状腺功能 亚临床甲状腺功能减退 检出率 

分 类 号：R581[医药卫生—内分泌]