中医内外同治综合疗法治疗女性更年期失眠的临床疗效  

Clinical Efficacy of TCM Comprehensive Therapy in Female Patients with Menopausal Insomnia

作　　者：谷宁飞[1] 陈会娟[1] 杜其敏 李国臣[1] 张君实 蔡增博 王志文 GU Ningfei;CHEN Huijuan;DU Qimin;LI Guochen;ZHANG Junshi;CAI Zengbo;WANG Zhiwen(Department of Emergency Services,Baoding No.1 TCM Hospital,Baoding 071000,China;Department of Chinese and Western Medicine,Affiliated Hospital of North China University of Technology,Tangshan 063000,China)

机构地区：[1]保定市第一中医院急诊科,河北保定071000 [2]华北理工大学附属医院中西医结合科,河北唐山063000

出　　处：《医学综述》2018年第24期4983-4987,共5页Medical Recapitulate

摘　　要：目的观察中医内服汤剂、外用耳穴、药枕综合疗法治疗女性更年期失眠的临床疗效。方法选择2015年12月至2016年12月保定市第一中医院收治的126例以失眠为主要表现且符合肝郁脾虚证的女性更年期失眠患者为研究对象,依据随机数字法分为观察和对照组,对照组(61例)采用西药艾司唑仑片治疗,观察组(65例)采用内服中药自拟疏肝补脾汤、外用耳穴贴敷、安神药枕的"内外同治"综合疗法。比较两组患者的临床疗效、治疗前后PSQI评分的变化。结果观察组总有效率高于对照组[92. 31%(60/65)比75. 41%(46/61)](P <0. 05)。治疗后,观察组入睡时间、睡眠效率、催眠药物、日间功能障碍和总分低于对照组[0. 5(0. 0,1. 0)分比1. 0(0. 5,1. 0)分、(1. 23±0. 49)分比(1. 52±0. 50)分、(0. 98±0. 88)分比(1. 30±0. 62)分、(0. 92±0. 75)分比(1. 43±0. 80)分、(7. 31±1. 80)分比(9. 07±1. 58)分],睡眠时间高于对照组[1. 0(1. 0,2. 0)分比1. 0(0. 5,2. 0)分](P <0. 05)。观察组复发率低于对照组[4. 76%(3/63)比20. 68%(12/58)](P <0. 05)。结论中医内外同治法综合治疗更年期失眠的临床疗效满意,安全、无不良反应。Objective To observe the clinical effect of Chinese medicine of internal decoction,external auricular cavity and occipital therapy on female patients with menopausal insomnia.Methods 126 menopausal insomnia women patients with insomnia as the main manifestation and liver depression and spleen deficiency admitted to Baoding No.1 TCM Hospital from Dec.2015 to Dec.2016 were included.According to the random number method,they were divided into an observation group(65 cases)and a control group(61 cases).The control group was treated with the western drug isazolam tablets.The observation group adopted the comprehensive therapy of internal Chinese medicine and external treatment comprehensive therapy of self-prepared Shugan Bupi soup,external auricular patch,and tranquilizing pillow.The clinical efficacy and PSQI score of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group[92.31%(60/65)vs 75.41%(46/61)](P<0.05).After treatment,time to fall asleep,sleep efficiency,hypnotics,diurnal dysfunction and total score in the observation group were lower than those of the control group[0.5(0.0,1.0)score vs 1.0(0.5,1.0)score,(1.23±0.49)score vs(1.52±0.50)score,(0.98±0.88)score vs(1.30±0.62)score,(0.92±0.75)score vs(1.43±0.80)score,(7.31±1.80)score vs(9.07±1.58)score],sleep time was longer than that in the control group[1.0(1.0-2.0)score vs 1.0(0.5-2.0)score](P<0.05).The recurrence rate of the observation group was lower than that of the control group[4.76%(3/63)vs 20.68%(12/58)](P<0.05).Conclusion The TCM comprehensive therapy has definite clinical effect on menopausal insomnia,which is safe,satisfactory and has no adverse effects.

关 键 词：更年期失眠 中医综合治疗 调肝补脾 耳穴贴敷 安神药枕 

分 类 号：R256.2[医药卫生—中医内科学]