罗库溴铵对肝癌手术全麻患者肌松效果的影响  

Effect of Rocuronium on Muscle Relaxation in Patients With Liver Cancer Undergoing General Anesthesia

作　　者：金明 JIN Ming(Department of Anesthesiology,Xiantao First People's Hospital,Xiantao Hubei 433000,China)

机构地区：[1]湖北省仙桃市第一人民医院麻醉科,湖北仙桃433000

出　　处：《中国继续医学教育》2019年第1期74-75,共2页China Continuing Medical Education

摘　　要：目的探究罗库溴铵对肝癌手术全麻气管插管术患者肌松效果及血流动力学的影响。方法选择我院行全麻气管插管麻醉的肝癌患者96例,按照随机数字表法将患者分成两组,每组48例;对照组采用苯磺顺阿曲库铵进行肌肉松弛,观察组则采用罗库溴铵作为肌松药;比较两组患者肌松效果、血流动力学指标的变化。结果观察组肌松起效时间较对照组短,差异有统计学意义(P <0.05),但两组肌松临床作用时间、恢复指数组间比较,差异无统计学意义(P> 0.05);给药5 min时,对照组心率明显升高、平均动脉压显著降低,且均明显高于/低于观察组,差异有统计学意义(P <0.05)。结论罗库溴铵对肝癌手术全麻气管插管术患者的肌松起效时间短,且对血流动力学的影响较小。Objective To investigate the effect of rocuronium on muscle relaxation and hemodynamics in patients undergoing liver cancer undergoing tracheal intubation under general anesthesia.Methods96patients with liver cancer who underwent general anesthesia and tracheal intubation anesthesia were randomly divided into two groups,48in each group.The control group was treated with benzuronium and atracurium for muscle relaxation,while the observation group was treated with rocuronium as a muscle relaxant.The effects of muscle relaxation and hemodynamic parameters were compared between the two groups.Results The onset time of muscle relaxation in the observation group was significantly shorter than that of the control group(P<0.05),but there was no significant difference between the two groups in clinical action time and recovery index(P>0.05).When5min was administered,the heart rate and mean arterial pressure in the control group were significantly higher/lower than the observation group(P<0.05).Conclusion Rocuronium had shorter onset time and lower hemodynamic effects on tracheal intubation in patients undergoing liver cancer surgery.

关 键 词：罗库溴铵 肝癌 全麻气管插管术 肌松效果 平均动脉压 心率 

分 类 号：R614[医药卫生—麻醉学]