新型不对称四苯乙烯衍生物的合成  

Synthesis of Novel Asymmetric Tetraphenylethylene Derivatives

作　　者：杨凌辉 曾旺 范建强 徐潇 金武松[1] 李贤英[2] 张灯青[1] Yang Ling-hui;Zeng Wang;Fan Jian-qiang;Xu Xiao;Jin Wu-song;Li Xian-ying;Zhang Deng-qing(College of Chemistry,Chemical Engineering and Biotechnology,Donghua University,Shanghai 201620;College of Environment Science and Engineering,Donghua University,Shanghai 201620)

机构地区：[1]东华大学化学化工与生物工程学院,上海201620 [2]东华大学环境科学与工程学院,上海201620

出　　处：《生物化工》2018年第6期78-80,共3页Biological Chemical Engineering

基　　金：上海市科技委(16JC1401900)

摘　　要：本文以1,4-二溴苯甲酮和二苯甲烷为起始原料合成化合物3[1, 1-二苯基-2, 2-二(4-溴苯基)乙烯]。化合物3与2-甲基-3-丁炔-2-醇发生Sonogashira偶联反应得到化合物2[4-(4-(1-(4-溴苯基)-2, 2-二苯基乙烯基)苯基)-2-甲基丁-3-炔-2-醇]。化合物2与三甲基乙炔基硅(TMSA)发生Sonogashira偶联反应得到化合物1[4-(4-(2, 2-二苯基-1-(4-((三甲硅基)乙炔基)苯基)乙烯基)苯基)-2-甲基丁-3-炔-2-醇],利用~1H NMR、^(13)C NMR和MALDI-TOF mass对化合物1的结构进行了表征。Compound3was synthesized by1,4-dibromobenzophenone and diphenylmethane,which was further treated with2-methyl-3-butyn-2-ol by Sonogashira coupling reaction to get compound2.Finally,compound2and TMSA with Snonogashira coupling reaction prepared for compound1,which was characterized by1H NMR,13C NMR,and MADIL-TOF mass.

关 键 词：Sonogashira偶联 四苯乙烯 合成 表征 

分 类 号：O625.1[理学—有机化学]