疾控档案在潍坊市2013—2017年疑似预防接种异常反应监测中的应用  

Application of the disease control file in the surveillance system of suspected vaccination abnormality in Weifang from 2013 to 2017

作　　者：周伟[1] 邱德山[1] Zhou Wei;Qiu Deshan(Weifang Center for Disease Control and Prevention,Weifang 261061,China)

机构地区：[1]潍坊市疾病预防控制中心,261061

出　　处：《中国医院统计》2018年第6期430-433,共4页Chinese Journal of Hospital Statistics

摘　　要：目的收集2013—2017年潍坊市疑似预防接种异常反应(adverse events following immunization,AEFI)的档案信息资料,评价AEFI监测系统运转状况。方法通过AEFI信息管理系统收集2013—2017年潍坊市AEFI个案数据,采用描述性流行病学方法对AEFI监测数据进行分析。结果 2013—2017年潍坊市共报告AEFI病例8 816例,报告发生率为50. 24/10万剂次;一般反应8 764例,占99. 41%;异常反应46例,占0. 52%;偶合症6例,占0. 07%。AEFI发现后48 h内报告率为99. 87%;<2岁共6 803例,占77. 17%;<1岁儿童4 568例,占51. 81%,发生例数较多的依次为9～月龄为795例,占17. 56%; 8～月龄685例,占15. 13%; 10～月龄540例,占11. 93%;发生间隔多在接种1 d内7 565例,占85. 81%。发生最多的临床症状为发热/红肿/硬结8 761例,占99. 38%。发生例数较多的是吸附无细胞百白破疫苗2 416例,占27. 40%。结论 2013—2017年潍坊市AEFI监测系统运转良好。Objective To collect archival information data of Adverse Events Following Immunization in Weifang from 2013 to 2017,and to evaluate the operation of AEFI monitoring system.Methods The index of AEFI data collected from the AEFI information management system was analyzed by descriptive epidemiological method in Weifang city from 2013 to 2017.Results Totally 8 816 AEFI cases were reported in Weifang city from 2013 to 2017,with the reported incidence rate 50.24/10 5,including 8 764 cases of general reaction accounting for 99.41%,46 cases of abnormal reaction accounting for 0.52%,and 6 cases of coincidence accounting for 0.07%.The reporting rate within 48 hours after the discovery was 99.87%.There were 6 803 cases under 2 years old,accounting for 77.17%,and 4 568 children under 1 year old accounting for 51.81%.There were 795 cases of 9 months old,accounting for 17.56%,685 cases of 4 months old accounting for 15.13%,and 540 cases of 10 months old accounting for 11.93%.And 7 565 cases occurred one day dafter vaccination accounting for 85.81%.The most frequent clinical symptoms were fever,local swelling,and induration in 8 761 patients accounting for 99.38%.The vaccine reported AEFI more frequent was DPT without cell vaccine in 2 416 cases,accounting for 27.40%.Conclusion The sensitivity of AEFI monitoring in Weifang is high.

关 键 词：疑似预防接种异常反应 疫苗 监测 档案信息 分析利用 

分 类 号：R197.2[医药卫生—卫生事业管理] R186[医药卫生—公共卫生与预防医学]