索利那新联合肾镜下EMS五代超声碎石清石术在膀胱结石腔内碎石治疗中的价值分析  

Study on the significance of Soliena combined with subarachnoid EMS fifth-generation ultrasonic lithotripsy in treatment of bladder lithotripsy

作　　者：曹雷涛 武立伟[1] 王娜[2] 陈平莲[3] 赵永辉[3] 孟伟红 CAO Lei-tao;WU Li-wei;WANG Na(Department of Urology and Vascular Surgery, Dezhou People's Hospital, Dingzhou Hebei 073000, China;Department of Ultrasound, Dezhou People's Hospital, Dingzhou Hebei 073000, China)

机构地区：[1]河北省定州市人民医院泌尿血管外科,河北定州073000 [2]河北省定州市人民医院超声科,河北定州073000 [3]河北省定州市人民医院病理科,河北定州073000

出　　处：《临床和实验医学杂志》2019年第1期92-94,共3页Journal of Clinical and Experimental Medicine

基　　金：河北省卫生和计划生育委员会课题(编号:20171496)

摘　　要：目的探讨索利那新联合肾镜下电子医疗系统(EMS)五代超声碎石术在膀胱结石治疗中的应用价值。方法回顾性研究,根据治疗方法将2015年5月至2017年3月河北省定州市人民医院就诊的130例膀胱结石患者分为两组,以单纯接受肾镜下EMS五代超声碎石术治疗者为对照组,以接受索利那新联合肾镜下EMS五代超声碎石术治疗者为联合组,每组各65例。比较两组患者手术治疗情况、术后膀胱功能恢复情况、膀胱功能改善情况和手术前后炎性因子变化情况。结果联合组患者手术时间(31. 56±11. 18) min、住院时间(8. 98±1. 15) d、术后24 h内膀胱痉挛次数(1. 19±0. 23)次/h及膀胱痉挛持续时间(0. 12±0. 08) s均低于对照组(36. 02±10. 21 min、10. 12±1. 12 d、2. 73±0. 16次/h、0. 31±0. 11 s),差异具有统计学意义(P <0. 05)。同时,入组时,两组患者间自我评价量表(OABSS)、国际前列腺症状评分(IPSS)、肿瘤坏死因子α(TNF-α)、C反应蛋白(CRP)及白细胞介素-6(IL-6)比较,差异无统计学意义(P> 0. 05),而术后3 d后,联合组OABSS评分(5. 53±1. 02分)、IPSS评分(3. 01±0. 85分)、TNF-α(15. 53±9. 05 nmol/L)、CRP(13. 19±8. 35μg/L)及IL-6(11. 81±9. 32 pg/ml)水平均低于对照组(7. 61±1. 38分、3. 93±0. 69分、22. 62±10. 22 nmol/L、20. 21±9. 12μg/L、15. 58±8. 19 pg/m),差异具有统计学意义(P <0. 05)。结论索利那新联合肾镜下EMS五代超声碎石术可有效改善膀胱结石的治疗效果及术后恢复情况。Objective To explore the signiicance of application of fifth-generation ultrasonic lithotripsy with soniuna combined endoscopic electronic medical system(EMS)in treatment of bladder stones.Methods A retrospective study was conducted.A total of 130 patients with bladder stones in this hospital during May 2015 to March 2017 were divided into 2 groups,patients in control group were treated with fifth generation ultrasonic lithotripsy and patients in combiination group were treated with Soliea combined with subarachnoid EMS fifth geberation ultrasonic lithotripsy,65 cases in each group.The condition of operation,the recovery of bladder function,the improvement of bladder fuunction and the change of bladder function and changes of inflammatory factors before and after surgery were compared between these 2 groups.Results In combination group,tthe operating time was 31.56±11 min,hoapitalzation time was 8.98±1.15d,times for bladder spasm 1.19±0.23 times/h,the duration for bladder spasm sustained 0.12±0.08 sec,all of them were lower than those of control group(36.02±10.21 min,10.12±1.12d,2.73±0.16 times/h and 0.31±0.11s hospitalization time(8.98±1.15)d,the number of bladder spasm(1.19±0.23)/h and the duration of bladder spasm(0.12±0.08)were all within 24 hours after operation.In comparison with the control group,the difference was statistically significant(P<0.05).At the same time,when enrolled,the difference between these two groups of patients in self-evaluation scale(OABSS),international prostate symptom scores(IPSS),tumor necrosis factor alpha(TNF-α),C-reactive protein(CRP)and interleukin-6(IL-6),the difference was not statistically significant(P>0.05),and 3 days after surgery,OABASS score(5.53±1.02),IPSS score(3.01±0.85),±TNF-α(15.53±9.05)nmol/L,CRP(13.19±8.35)μg/L and IL-6(11.81±9.32)pg/ml water in combination group were lower than those of control group(7.61±1.38,3.93±0.69,22.62±10.22 nmol/L,20.21±9.12μg/L,15.58±8.19 pg/m),and the difference was statistically significant(P<0.05).Conclusion

关 键 词：膀胱结石 腔内碎石 索利那新 肾镜 电子医疗系统 五代超声 

分 类 号：R699.5[医药卫生—泌尿科学]