光叶子花的化学成分研究  

Chemical Constituents from Bougainvillea glabra

作　　者：张冉 刘加祥 段金超 范彬彬 宋启示[1] 张玉梅[1] ZHANG Ran;LIU Jiaxiang;DUAN Jinchao;FAN Binbin;SONG Qishi;ZHANG Yumei(Key Laboratory of Tropical Plant Resource and Sustainable Use,Xishuangbanna Tropical Botanical Garden,Chinese Academy of Sciences,Kunming 650223,China;University of Chinese Academy of Sciences,Beijing 100049,China;Puer University,Puer 665000,China)

机构地区：[1]中国科学院西双版纳热带植物园,热带植物资源可持续利用重点实验室,云南昆明650223 [2]中国科学院大学,北京100049 [3]普洱学院,云南普洱665000

出　　处：《云南农业大学学报（自然科学版）》2018年第6期1175-1179,共5页Journal of Yunnan Agricultural University:Natural Science

基　　金：云南省应用基础研究重点项目(2014FA043);中国科学院个性化药物战略性先导科技专项(XDA12040321);中国科学院战略生物资源服务网络计划活性天然化合物发现、评价与转化项目(Y45J051K01);云南省中青年学术技术带头人后备人才项目(2010CI048).

摘　　要：【目的】为进一步开发光叶子花的药用价值,对光叶子花进行了化学成分研究。【方法】通过硅胶、Sephadex LH-20凝胶及RP-C18反相硅胶等色谱柱分离纯化,并运用MS和NMR等波谱学方法鉴定化合物的化学结构。【结果】从光叶子花花的工业甲醇提取物中分离得到6个化合物,分别鉴定为:D-松醇(1)、菠甾醇(2)、3-O-[6′-O-palmitoyl-β-D-glucosyl]-spinasta-7,22-diene (3)、胡萝卜苷(4)、isorhamnetin-3-O-(6′′-O-E-feruloyl)-β-D-galactopyranoside (5)、isorhamnetin-3-O-β-D-glucopyranoside (6)。【结论】光叶子花的化学成分研究较少,本文较深入地对其花的化学成分进行了研究,化合物2、5和6均为首次从该植物中分离得到,在一定程度上丰富了光叶子花的化学成分研究,有利于进一步开发其药用价值。[Purpose]The study on the chemical constituents of the flower of Bougainvillea glabra Choisy was to exploit its medicinal value.[Method]Compounds were isolated by column chromatography of silica gel,Sephadex LH-20and RP-C18,and their structures were identified by spectral methods(MS and NMR).[Result]Six compounds were finally isolated and identified as D-pinitol(1),α-spinaterol(2),3-O-[6′-O-palmitoyl-β-D-glucosyl]-spinasta-7,22-diene(3),daucosterol(4),isorhamnetin-3-O-(6′′-O-E-feruloyl)-β-D-galactopyranoside(5),and isorhamnetin-3-O-β-D-glucopyranoside(6),respectively.[Conclusion]There are few reports on the chemical constitents of B.glabra,and we extensively investigated the chemical constituents of its flower.Compounds 2,5 and 6 were isolated from this species for the first time.To a certain extent,our study enriched the chemical constituents of B.glabra.This work will be conducive to the exploiting of the medicinal value of B.glabra.

关 键 词：光叶子花 化学成分 结构鉴定 

分 类 号：R284.1[医药卫生—中药学]