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作 者:陈鑫[1] 张佳 牛洁[1] 刘亚东[1] 景娟[1] CHEN Xin;ZHANG Jia;NIU Jie;LIU Yadong;JING Juan(Department of Clinical Laboratory,Stomatological Hospital of Xi′an Jiaotong University,Xi′an,Shaanxi 710004,China;Department of Pathology,Stomatological Hospital of Xi′an Jiaotong University,Xi′an,Shaanxi 710004,China)
机构地区:[1]西安交通大学口腔医院检验科,西安710004 [2]西安交通大学口腔医院病理科,西安710004
出 处:《检验医学与临床》2019年第1期35-37,共3页Laboratory Medicine and Clinic
基 金:西安交通大学口腔医院院青年科研基金资助项目(201703)
摘 要:目的探讨口腔洁治术患者感染性标志物检测的临床应用价值,并完善口腔健康的管理系统。方法选取该院牙周病科和口腔预防保健科2016―2017年就诊的欲行口腔洁治术患者15 836例。患者血液标本采用酶联免疫吸附(ELISA)法检测其血清乙型肝炎表面抗原(HBsAg)、丙型肝炎抗体(抗-HCV)、梅毒抗体(抗-TP)、人类免疫缺陷病毒抗体(抗-HIV)。对患者病例资料及4项感染性标志物的检测结果进行总结,并进行统计学分析。结果 2016―2017年15 836例患者总阳性为866例,阳性率为5.47%,总阳性率各年之间比较,差异无统计学意义(P>0.05)。其中男性阳性患者487例,阳性率为3.08%;女性阳性患者为379例,阳性率为2.39%,男、女性阳性率比较,差异无统计学意义(P>0.05)。4项感染性标志物阳性率从高到低分别为HBsAg(3.89%)、抗-TP(0.73%)、抗-HCV(0.71%)、抗-HIV(0.14%)。不同年龄段患者的总阳性率呈不规则分布。结论口腔洁治术患者进行感染性标志物检测,可以明确血液传播,有利于解决是否为医源性感染而引起的医疗纠纷,保护其他患者的安全及防止医务人员职业暴露。Objective To study and evaluate the clinical application value of infectious markers detection before dental scaling,and complete the management system of oral health.Methods A total of 15 836 patients from department of periodontology and preventive dentistry in thel hospital of stomatology Xi′an Jiaotong University were selected as the subjects of the study form 2016 to 2017.Serum HBsAg,anti-HCV,anti-TP and anti-HIV were detected by ELISA in all patients.The data of all patients and the detection results of four infectious markers were summarized and analyzed with statistics.Results There were 866 positive patients in 15 836 patients from 2016 to 2017,with a positive rate of 5.47%and no statistically significant difference in total positive rate.Among them,487 cases were male and 3.08%were positive.There were 379 female positive cases,and the positive rate was 2.39%,and there was no statistically significant difference in male and female positive rates.The positive rates of the four infectious markers were HBsAg(3.89%),anti-TP(0.73%),anti-HCV(0.71%)and anti-HIV(0.14%).The total positive rates in different age groups were randomly distributed.Conclusion Infective markers detection before dental scaling can be clearly defined the specific situation of infectious diseases transmitted by blood,helps to solve for iatrogenic infection caused by medical disputes,to protect the other patient safety and to prevent medical staff occupational exposure.At the same time,it has important guiding effect on preventing cross infection,it can be used as reference for outpatient treatment of other demonstrative effect,and its clinical value is significant.
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