老年慢性阻塞性肺疾病并发呼吸衰竭采用纳洛酮与无创呼吸机联合治疗的研究  

Study on the Combination of Naloxone and Non-Invasive Ventilator in Elderly Patients with Chronic Obstructive Pulmonary Disease Complicated with Respiratory Failure

作　　者：蒋云书 王淑霞[1] JIANG Yun-shu;WANG Shu-xia(Liaocheng Second People's Hospital,Liaocheng,Shandong Province,252000 China)

机构地区：[1]聊城市第二人民医院,山东聊城252000

出　　处：《系统医学》2018年第23期35-37,共3页Systems Medicine

摘　　要：目的研究分析老年慢性阻塞性肺疾病并发呼吸衰竭采用纳洛酮与无创呼吸机联合治疗的效果。方法该次研究采用实验性研究,病例筛选起止时间2017年2月—2018年4月份,筛选病例98例,按照数字随机法分成两组,常规治疗基础上无创组使用无创呼吸机,联合组在无创治疗上使用纳洛酮,两组患者治疗效果以及治疗前后动脉血气分析情况对比。结果联合组治疗有效率为97.96%,与无创组87.76%的治疗有效率比较差异有统计学意义(χ~2=10.119,P<0.05)。经治疗后,两组动脉血气分析水平较之前均有不同程度的改善,组间比较差异有统计学意义(t=7.316,7.162,8.094,P<0.05)。结论老年慢性阻塞性肺疾病并发呼吸衰竭采用纳洛酮与无创呼吸机联合治疗效果较好,有效改善患者的动脉血气分析,改善呼吸衰竭情况,治疗效果显著,值得推广应用。Objective To study the effect of naloxone combined with non-invasive ventilator in the treatment of elderly patients with chronic obstructive pulmonary disease complicated with respiratory failure. Methods The experimental study was conducted in this study. The screening time of the cases was from February 2017 to February 2018. 98 cases were screened and divided into two groups according to the numerical randomization method. The non-invasive ventilator was used in the non-invasive group based on conventional treatment. Naloxone was used in the combined group with non-invasive treatment, and the therapeutic effects of the two groups of patients and the analysis of arterial blood and qi before and after treatment were compared. Results The effective rate of the combined group was 97.96%, which was statistically significant compared with the effective rate of 87.76% in the non-invasive group (χ^2=10.119, P<0.05). After treatment, the arterial blood gas analysis levels of the two groups were improved to some extent compared with the previous ones. The difference between the two groups was statistically significant(t=7.316, 7.162, 8.094, P<0.05). Conclusion Older chronic obstructive pulmonary disease complicated with respiratory failure is better with naloxone combined with non-invasive ventilator. It can effectively improve the arterial blood qi analysis and improve respiratory failure. The therapeutic effect is significant and worthy of popularization and application.

关 键 词：老年慢性阻塞性肺疾病 并发 呼吸衰竭 纳洛酮 无创呼吸机 联合治疗 

分 类 号：R563[医药卫生—呼吸系统]