NCPAP治疗小儿重症肺炎的临床效果观察  

Clinical effect observation of NCPAP on children with severe pneumonia

作　　者：高建波[1] 解发雨[1] 郑伟伟[1] 李娜[1] GAO Jianbo;XIE Fayu;ZHENG Weiwei;LI Na(Jiyuan Shi People's Hospital, Jiyuan Henan 459000, China)

机构地区：[1]济源市人民医院,河南济源459000

出　　处：《中国民康医学》2018年第24期31-33,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察经鼻持续气道正压通气(NCPAP)治疗小儿重症肺炎的临床效果。方法:选取60例重症肺炎患儿作为观察对象,依据随机数字表法将其分为对照组和观察组各30例,两组均在综合治疗基础上,对照组经鼻导管吸氧治疗,观察组采用NCPAP治疗。比较两组临床症状和体征改善时间、临床效果及治疗前后心功能指标情况。结果:观察组心率恢复正常时间、紫绀消失时间、呼吸困难消失时间及肺部啰音消失时间均明显短于对照组,差异有统计学意义(P<0.05);观察组治疗有效率为96.67%(29/30),明显高于对照组的80.00%(24/30),差异有统计学意义(P<0.05);治疗后观察组左室射血分数(LVEF)、房室瓣E与A峰比值(E/A)、心脏指数(CI)明显高于对照组,左室舒张末期内径(LVDS)明显低于对照组,差异均有统计学意义(P<0.05);治疗后观察组氧分压(PO2)及二氧化碳分压(PCO2)明显优于对照组,差异有统计学意义(P<0.05)。结论:在综合治疗基础上采用经鼻持续气道正压通气治疗小儿重症肺炎的临床效果优于经鼻导管吸氧治疗效果。Objective: To study clinical effects of nasal continuous positive airway pressure (NCPAP) on children with severe pneumonia.Methods: 60 children with severe pneumonia were selected as the observation subjects.According to the random number table method,they were divided into control group ( n =30) and observation group ( n =30).Based on the comprehensive treatment,the control group received oxygen therapy through the nasal catheter,while the observation group was given the NCPAP treatment.The improvement time of clinical symptoms and signs,clinical effects and cardiac function indexes before and after the treatment were compared between the two groups.Results: The time of heart rate recovery,the disappearance time of cyanosis,the disappearance time of dyspnea and the disappearance time of lung rales were significantly shorter in the observation group than in the control group,and the differences were statistically significant (P<0.05).The effective rate of observation group was 96.67%(29/30),which was significantly higher than the control group of 80.00%(24/30),and the difference was statistically significant (P<0.05).After the treatment,the left ventricular ejection fraction (LVEF),atrioventricular valve E and A peak ratio (E/A),and (heart index) CI were significantly higher in the observation group than in the control group,the left ventricular end-diastolic diameter (LVDS) was significantly lower than the control group,and the differences were statistically significant (P<0.05).After the treatment,the oxygen (PO2 ) and carbon dioxide partial pressure (PCO2 ) in the observation group were significantly better than those in the control group,and the differences were statistically significant (P<0.05).Conclusions: In the treatment of the children with severe pneumonia,NCPAP based on the comprehensive treatment is superior to single oxygen therapy through the nasal catheter.

关 键 词：重症肺炎 NCPAP 心功能 临床效果 

分 类 号：R563.1[医药卫生—呼吸系统]