观察联合抗凝治疗在心源性脑梗塞中的应用效果分析  

Observation and analysis of the effect of combined anticoagulant therapy in patients with cardiogenic cerebral infarction

作　　者：彭铮[1] 吕建[1] Peng Zheng;Lv Jian(Department of Neurology,Xinmin people' s Hospital,Liaoning Province,Xinmin,Liaoning,110300,China)

机构地区：[1]辽宁省新民市人民医院神经内二科,辽宁新民110300

出　　处：《当代医学》2019年第2期117-119,共3页Contemporary Medicine

摘　　要：目的观察联合抗凝治疗在心源性脑梗塞中的应用效果。方法选取2015年12月至2017年8月收治的心源性脑梗死患者78例进行分组研究,按照随机数字表法的分组方法将其分为对照组和治疗组两组,对照组39例采用常规方法进行治疗,治疗组39例在对照组治疗基础上联合抗凝治疗,比较治疗前后两组神经功能缺损、日常生活能力、运动功能改善效果、临床疗效和并发症的差异。治疗后两组NIHSS评分明显低于治疗前,BI(the Barthelindex of ADL,Barthel指数)、FMA(Fugl-Meyer Assessment,Fugl-Meyer评测法)评分明显高于治疗前,组间进行统计分析。结果治疗组上述指标均优于对照组,差异有统计学意义(P<0.05);对照组患者的临床治疗总有效率明显高于对照组,两组之间表现出的显著差异具有统计学意义(P<0.05);在并发症发生率比较上,治疗组显著低于对照组,组间经比较,差异存在统计学意义(P<0.05)。结论联合抗凝治疗对提高心源性脑梗死患者的临床治疗效果,改善神经功能、日常生活运动能力和降低并发症发生率具有重要意义,值得在临床中全面普及推广。Objective To observe the effect of combined anticoagulant therapy in cardiogenic cerebral infarction.Methods A total of 78 patients with cardiogenic cerebral infarction admitted from December 2015 to August 2017 were enrolled in a group study.They were divided into two groups according to the random number table method.The control group was used in 39 cases.Methods:39 patients in the treatment group were treated with anticoagulant therapy on the basis of the control group.The differences of neurological deficit,daily living ability,motor function improvement,clinical efficacy and complications were compared before and after treatment.After treatment,the NIHSS scores of the two groups were significantly lower than those before treatment.The scores of BI(the Barthel index of ADL,Barthel index)and FMA(Fugl-Meyer Assessment,Fugl-Meyer)were significantly higher than those before treatment.Results The above indexes were better than the control group in the treatment group,the difference was statistically significant(P<0.05).The total effective rate of clinical treatment in the control group was significantly higher than that in the control group.The significant difference between the two groups was statistically significant(P<0.05);in the comparison of the incidence of complications,the treatment group was significantly lower than the control group,the difference between the groups was statistically significant(P<0.05).Conclusion Combined anticoagulant therapy is of great significance in improving the clinical therapeutic effect of patients with cardiogenic cerebral infarction,improving neurological function,daily exercise capacity and reducing the incidence of complications.It is worthy of popularization in clinical practice.

关 键 词：心源性脑梗塞 联合抗凝治疗 应用效果 

分 类 号：R743.3[医药卫生—神经病学与精神病学]