调查骨科内固定取出术预防使用抗菌药物与否的差异  

Study on the preventive use of antibiotics in removal surgery for internal fixation

作　　者：黄建权[1] 许姜姜[2] 杨巧玲 高洁 孙华君[1] HUANG Jianquan;XU Jiangjiang;YANG Qiaoling;GAO Jie;SUN Huajun(Department of Pharmacy,Shanghai Children′s Hospital,Shanghai 200062,China;Hospital Infection Office,Shanghai Children′s Hospital,Shanghai 200062,China)

机构地区：[1]上海市儿童医院药学部,上海200062 [2]上海市儿童医院院感办,上海200062

出　　处：《药学实践杂志》2019年第1期74-76,共3页Journal of Pharmaceutical Practice

基　　金：上海市卫生计生系统重要薄弱学科建设计划(2016ZB0305-01)

摘　　要：目的考察骨科内固定取出术预防使用抗菌药物与否的效果差异。方法回顾性分析上海市儿童医院骨科2016—2017年间,择期内固定取出术患儿的性别、年龄、血常规检查数据、是否预防使用抗菌药物、是否继发切口感染和术后住院时间等数据。结果预防使用抗菌药物组(71例)与未用药组(350例)患儿的术后平均住院时间分别为(1.80±1.24)d和(1.27±0.61)d,差异有统计学意义(P<0.05)。结论是否预防使用抗菌药物与切口感染无关,建议逐步纠正临床医生的预防用药行为,降低骨科择期内固定取出术预防使用抗菌药物的比例。Objective To investigate the preventive use of antibiotics for internal fixation as selective removal surgery during perioperative period.Methods The sex,age,routine blood examination data,preventive medications,secondary incision infection and postoperative hospital stay for the patients underwent selective removal surgery for internal fixation from July 2015 to June 2017 were analyzed.Results The average postoperative hospitalization time for the preventive medication group(n=71)and the untreated group(n=350)were(1.80±1.24)days and(1.27±0.61)days.This difference was statistically significant(P<0.05).Conclusion Preventive antibiotics use is not related to incision infections.It is recommended to correct the current behavior of the preventive drug use.The preventive antibiotics use in selective removal surgery for internal fixation in the Department of orthopedics needs to be reduced.

关 键 词：清洁手术 内固定 预防用药 抗菌药物 

分 类 号：R969.3[医药卫生—药理学]