乌头属中药多糖研究进展  

Research Progress on Polysaccharides of Aconitum Medico-Plants

作　　者：刘淑萍[1] 张新渐 王洪云[2] 曾忠兰 张建英[1] 左爱学[1] LIU Shuping;ZHANG Xinjian;WANG Hongyun;ZENG Zhonglan;ZHANG Jianying;ZUO Aixue(Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China 650500;Baoshan College of Traditional Chinese Medicine, Baoshan, Yunnan, China 678000)

机构地区：[1]云南中医学院,云南昆明650500 [2]保山中医药高等专科学校,云南保山678000

出　　处：《中国药业》2019年第3期1-6,共6页China Pharmaceuticals

基　　金：云南省应用基础研究计划面上项目[2015FB155];云南民族大学民族药资源化学国家民委-教育部重点实验室开放基金[MZY1503]

摘　　要：乌头属植物是重要的药用植物资源,已经开发出草乌甲素等二萜生物碱类无成瘾性镇痛药。除二萜生物碱外,多糖亦是乌头属植物的主要活性成分。乌头属植物多糖具有增强免疫、降血糖、抗炎、抗肿瘤、抗氧化、降胆固醇等生物活性。该文对1986年以来文献报道的乌头属植物多糖的提取分离、含量测定及生物活性研究进行综述,为乌头属植物的研究开发提供参考。Aconitum plants are important medicinal plant resources. Diterpenoid alkaloids such as bulleyaconitine A have been developed as non - addictive analgesics. In addition to diterpenoid alkaloids, polysaccharides are also the main active ingredients of Aconitum plants. The polysaccharides of Aconitum plants have the bioactivity of enhancing immunity, lowering blood sugar, anti - inflammation, anti - tumor, anti - oxidation and lowering cholesterol. In this paper, the extraction, separation, content determination and bioactivity of Aconitum polysaccharides reported in the literature since 1986 were reviewed, which could provide a reference for the research and development of Aconitum plants.

关 键 词：乌头属 多糖 提取分离 含量测定 生物活性 进展 

分 类 号：R932[医药卫生—生药学] R284.2[医药卫生—药学]