东莞外来女性产后抑郁症甲状腺激素与其社会心理学因素相关性研究  

Correlational study of socio-psychological factors between the thyroid hormone of postpartum depression among the female immigrants in Dongguan

作　　者：曾小华 裴丽 刘喻 任兰振 陈桓练 黄纳新 黄爱清 张丽娟 李换霞 曾丽萍 荣秀花 聂谊斌 ZENG Xiaohua;PEI Li;LIU Yu;REN Lanzhen(Dong Hua Hospital,Sun Yat-sen University,Dong Guan 523000,China)

机构地区：[1]中山大学附属东华医院,广东东莞523000 [2]广东理文造纸有限公司,广东东莞523000

出　　处：《现代医院》2019年第1期57-61,共5页Modern Hospitals

基　　金：东莞市医疗卫生单位科技计划项目(编号:20131051010249)

摘　　要：目的通过东莞外来女性产后抑郁症(PPD)患者的研究,探讨患者甲状腺激素水平与其社会心理学因素的相关性。方法选择东莞外来女性产后4～6周的产妇6 000人,筛选出爱丁堡产后抑郁量表分数≥13分产妇200人,进行社会心理学因素调查:生活事件量表测定、特质应对方式测定、Lock-Wollance婚姻调适测定,并同时进行生物学因素测定:抽血化验FT3、FT4、TSH。结果东莞外来女性PPD患者的生活事件、婚姻状况、应对方式及其FT3、FT4、TSH 3项生物学指标的相关性分析分组比较显示,(1)患者年龄(~~aP)和生物学因素中的FT3值[年龄<30岁组和≥30岁组对比:4. 510(4. 030,5. 000) pmol/L VS 4. 047±0. 568 pmol/L]相关性有统计学意义(~aP <0. 05);(2)患者的分娩方式(~aP)和生物学因素中的TSH值[正常分娩组和剖宫产组对比:1. 028(0. 815,1. 325 m Iu/L vs 1. 690(1. 200,2. 080) m Iu/L]相关性有统计学意义(~aP <0. 05);(3)低于5 000元收入的母亲样本中,患者的收入和生物学因素中的FT3(~aP)、FT4(~bP)、TSH(~aP)值[收入3 000元以下组和3 000～5 000元组、> 5 000元组对比:(1)FT3 4. 560(4. 030,4. 920) pmol/L vs 3. 990(3. 815,4. 565) pmol/L vs 4. 655(4. 330,5. 620) pmol/L。(2)FT4 12. 961±1. 920 pmol/L vs13. 969±2. 169 pmol/L vs 16. 607±2. 557 pmol/L。(3)TSH 1. 330(1. 080,3. 260) m Iu/L vs 1. 720(1. 350,1. 950) m Iu/L vs 0. 989(0. 772,1. 290) m Iu/L]有统计学意义(~aP <0. 05,~bP <0. 01);(4)患者的甲状腺激素与婚姻状况及应对方式的相关性分析分组比较显示差异无统计学意义(P> 0. 05)。结论 (1)东莞外来女性的产妇年龄30岁是FT3的高危因素及数值,剖宫产分娩方式是TSH的高危因素,收入5 000元是FT3、FT4、TSH的高危因素及数值;(2)大部分东莞外来女性都能从容面对婚姻和压力,婚姻状况和应对方式与甲状腺激素的相关性无显著性差异;(3)东莞外来女性产后抑郁症不会影响到甲状腺激素水平,但可以作为预测因素;Objective Through the study of postpartum depression among the female immigrants in Dongguan,the paper intends to study on the correlation between the socio-psychological factors,thyroid hormone in patients.Method Among the 6000 materials for 4-6 weeks postpartum from the female immigrants in Dongguan,200 immigrants are selected by the Edinburgh postnatal depression scale score≥13 maternal,and investigated by social and psychological factors:Determination of life events scale,coping determination determination,Lock-Wollance marital adjustment,Determination and biological factors:blood tests FT3、FT4、TSH.Results ①Correlation analysis of life status,marriage,coping style betweenthe biological factors FT3、FT4、TSH of postpartum depression among the female immigrants in Dongguanshowsthat correlational study of the maternal age(^aP)and the biological factors of FT3[<30 years age group vs≧30 years age group:4.510(4.030,5.000)pmol/L VS 4.047±0.568 pmol/L],there are statistically significant differences(^aP<0.05);②Correlational study of thepatients’ delivery way(^aP)and the biological factors of TSH[normal delivery group vs cesarean section group:1.028(0.815,1.325 mIu/L vs 1.690(1.200,2.080) mIu/L],there are statistically significant differences(^aP<0.05,);③In the mother sample with less than 5000 yuan income,correlational study of thepatients’ income and the biological factors of FT3(^aP),FT4(^bP),TSH(^aP)[income<3000 yuan group vs income 3000-5000 yuan group vs income>5000 yuan group:①FT3 4.560(4.030,4.920)pmol/L vs 3.990(3.815,4.565)pmol/L vs 4.655(4.330,5.620) pmol/L;②FT4 12.961±1.920 pmol/L vs 13.969±2.169 pmol/L vs 16.607±2.557 pmol/L;③TSH 1.330(1.080,3.260) mIu/L vs 1.720(1.350,1.950) mIu/L vs 0.989(0.772,1.290) mIu/L],there are statistically significant differences(^aP<0.05,^bP<0.01);4.There was no significant difference in the relationship between thyroid hormone and marital status and coping style (P>0.05).Conclusion ①The age of the patient is 30 years old is the high risk factor

关 键 词：东莞外来女性 产后抑郁症 生活状况 婚姻状况 应对方式 甲状腺激素 相关性 

分 类 号：R714[医药卫生—妇产科学]