侵入性生理学指标评估冠状动脉狭窄功能意义的研究方法及进展  

Invasive Physiological Indices to Assess Functional Significance of Coronary Artery Stenosis

作　　者：王申[1] 姚道阔[1] 李东宝[1] WANG Shen;YAO Daokuo;LI Dongbao(Department of Cardiology,Youyi Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院心脏中心,北京100050

出　　处：《心血管病学进展》2019年第1期1-5,共5页Advances in Cardiovascular Diseases

摘　　要：目前生理学测量方法用于评估导管室冠状动脉病变越来越常用,这种应用是基于循证学证据的并且已获得临床指南推荐。血流储备分数是目前确定冠状动脉病变是否具有功能意义的金标准,并用于指导血运重建。而且,陆续提出了其他几种生理学测量方法正在作为分数流量储备的替代方案。在本综述中,除了血流储备分数之外,还回顾和总结了冠状动脉循环系统其他有创性功能指标的主要特征。现重点讨论它们的优缺点,以及目前支持其使用的证据。Physiological measurements are increasingly used to evaluate coronary luminal lesions.This application is based on evidence-based evidence and has been recommended by clinical guidelines.The blood flow reserve score is currently the gold standard for determining whether coronary artery disease has functional significance and is used to guide revascularization.What s more,several other physiological measurement methods are being proposed as an alternative of fractional flow reserve.The aim of this review is to provide a comprehensive discussion for the most common invasive physiological indices to assess coronary lesions,including their advantages,disadvantages and the evidence that supports their use.

关 键 词：冠状动脉生理学 血流储备分数 静息生理指标 冠状动脉血流储备 

分 类 号：R541.4[医药卫生—心血管疾病]