早孕期胎儿颈项透明层厚度和静脉导管频谱检查对双胎输血综合征的预测价值  

Fetal Nuchal Translucency Thickness and Ductus Venosus Spectrum Examination in Predicting Twin-twin Transfusion Syndrome During Early Pregnancy

作　　者：何蓉[1] 杨伟清[2] 张红霞[3] HE Rong;YANG Weiqing;ZHANG Hongxia(Department of Healthcare,Zhuhai Maternal and Child Health Hospital,Zhuhai 519000,China)

机构地区：[1]珠海市妇幼保健院妇保科,广东珠海519000 [2]珠海市妇幼保健院超声科,广东珠海519000 [3]珠海市妇幼保健院产科,广东珠海519000

出　　处：《中国医学影像学杂志》2019年第1期38-41,共4页Chinese Journal of Medical Imaging

基　　金：广东省医学科学技术研究基金(B2016113)

摘　　要：目的探讨早孕期胎儿颈项透明层(NT)厚度和静脉导管(DV)频谱异常在预测双胎输血综合征(TTTS)的意义。资料与方法回顾性分析2015年10月—2017年9月珠海市妇幼保健院产科单绒双羊双胎347例,NT、DV频谱超声检查时间为孕11～14周。其中正常单绒毛膜性双胎334例,TTTS双胎13例。比较正常组与TTTS组11～14周2个胎儿NT值、NT差值及DV频谱。结果 TTTS组双胎NT差值为(0.71±0.09)mm,正常双胎NT差值为(0.28±0.01)mm,两组比较,差异有统计学意义(P<0.05)。TTTS组DV频谱异常8例,正常组4例,两组比较,差异有统计学意义(P<0.05)。结论早孕期2个胎儿NT差值和DV频谱异常均对预测TTTS有一定意义,两者联合对预测TTTS风险更有意义。Purpose To investigate the significance of fetal nuchal translucency(NT)thickness and ductus venosus(DV)spectrum abnormality in predicting twin-twin transfusion syndrome(TTTS)during early pregnancy.Materials and Methods A retrospective analysis of 347 cases of monochorionic and double amniotic sac twin pregnancies in Zhuhai Maternal and Child Health Hospital from October 2015 to September 2017.The time of ultrasound examination of NT and DV was taken between 11-14 weeks of gestation.According to their results,334 cases were normal monochorionic twins and 13 cases were TTTS twins.Compared the fetal NT value,NT difference and DV spectrum between the normal group and the TTTS group for 11-14 weeks of gestation.Results The difference of twin NT in the TTTS group was(0.71±0.09)mm,which was(0.28±0.01)mm in the normal group.The difference between the two groups was statistically significant(P<0.05).There were 8 cases with abnormal DV spectrum in the TTTS group which compared to 4 cases with abnormal DV spectrum in the normal group.The difference between the two groups was statistically significant(P<0.05).Conclusion Both the two NT differences and DV spectrum abnormalities in early pregnancy have certain significance for predicting TTTS.The joint of the two could be more meaningful for predicting TTTS risk.

关 键 词：双胎输血综合征 超声检查 产前 静脉 妊娠初期 胎儿 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]