MR在脑深部电刺激术治疗帕金森病中的应用价值  

Application Value of MR in Treatment of Parkinson's Disease Using the Deep Brain Stimulation

作　　者：季丽雅 王建伟 孙涛[2] 王敏[2] JI Liya;WANG Jianwei;SUN Tao;WANG Min(Department of Radiology,The BenQ Medical Center,Nanjing Jiangsu 210021,China;Department of Radiology,The First Affiliated Hospital with Nanjing Medical University,Nanjing Jiangsu 210029,China)

机构地区：[1]南京明基医院放射科,江苏南京210021 [2]南京医科大学第一附属医院放射科,江苏南京210029

出　　处：《中国医疗设备》2019年第2期89-91,95,共4页China Medical Devices

摘　　要：目的探讨MR在脑深部电刺激术(Deep Brain Stimulation,DBS)治疗帕金森病(Parkinson’s Disease,PD)中的应用价值。方法对30例PD患者在DBS术前行3 T颅脑MR扫描,术中行1.5 T颅脑MR扫描,扫描序列采用常规颅脑MR序列和SWI序列。由两位放射科医师对MR图像进行评估,采用秩和检验比较各序列的图像质量。结果丘脑底核(SubthalamicNucleus,STN)在3 T-SWI、3 T-T2WI和1.5 T-T2WI序列上显示为双凸透镜低信号影,在3 T-T1WI上显示不清;经比较,四组序列的图像质量有统计学差异,STNs在3 T-SWI上显示最清晰(χ2=88.952,P<0.001)。结论相较于常规T2WI和T1WI序列,3 T-SWI是显示丘脑底核的最佳序列,MR对于DBS手术靶点核团的定位有较高的临床应用价值。Objective To explore the application value of MR in the treatment of Parkinson’s disease(PD)using deep brain stimulation(DBS).Methods 3 T magnetic resonance imaging(MRI)was performed on 30 PD cases before DBS and 1.5 T MRI was performed during the operation.The routine brain MR sequences and the susceptibility weighted imaging(SWI)were adopted.The qualities of MR images were evaluated by 2 radiologists.The rank sum test was adopted to compare the image quality of each sequence.Results The subthalamic nucleus(STNs)were visualized as hypointense,biconvex lens-shaped structures on the 3T-SWI,3 T-T2WI and 1.5 T-T2WI images,while they couldn’t be visualized clearly on 3 T-T1WI images.After comparisons,there were statistically significant differences between the image qualities of 4 groups.STNs were most clearly visualized on 3 T-SWI(χ2=88.952,P<0.001).Conclusion Compared to the routine T2WI and T1WI sequences,3 T-SWI is the optimal sequence to identify STNs.MR has a high clinical application value in localizing target nucleus of DBS.

关 键 词：磁共振 脑深部电刺激术 帕金森病 

分 类 号：R445.2[医药卫生—影像医学与核医学]