麒麟竭果壳化学成分的研究  

Chemical constituents from the shells of Daemonorops draco

作　　者：朱仝飞[1,2] 孙庆文 闫志慧[1,2] 李萍[1,2] ZHU Tong-fei;SUN Qing-wen;YAN Zhi-hui;LI Ping(Chongqing Medical and Pharmaceutical College,Chongqing 401331,China;Chongqing Engineering Research Center of Pharmaceutical Sciences,Chongqing 401331,China;Guiyang College of Traditional Chinese Medicine,Guizhou 550025,China)

机构地区：[1]重庆医药高等专科学校,重庆401331 [2]重庆市药物制剂工程技术研究中心,重庆401331 [3]贵阳中医学院,贵州贵阳550025

出　　处：《中成药》2019年第2期337-340,共4页Chinese Traditional Patent Medicine

基　　金：重庆市教委科学技术研究项目(KJ1502701);重庆市卫生计生委中医药科技项目(ZY201702127);重庆医药高等专科学校自然科学项目(ygz2015114)

摘　　要：目的研究麒麟竭Daemonorops draco Bl.果壳的化学成分。方法麒麟竭果壳甲醇提取液采用硅胶、重结晶、Sephadex LH-20、制备薄层色谱进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到10个化合物,分别鉴定为β-谷甾醇(1)、豆甾醇(2)、18-降去氢松香酸-4α,7β-二醇(3)、去氢松香酸(4)、7α-羟基去氢松香酸(5)、2β-羟基海松酸(6)、香草醛(7)、儿茶素(8)、对羟基苯甲醛(9)、胡萝卜苷(10)。结论所有化合物均为首次从该植物果壳中分离得到。AIM To study the chemical constituents from the shells of Daemonorops draco Bl.METHODS The methanol extract from the shells of D.draco was isolated and purified by silica column,recrystallization,Sephadex LH-20 and preparative thin layer chromatography,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Ten compounds were isolated and identified asβ-sitosterol(1),stigmasterol(2),18-norabieta-8,11,13-triene-4α,7β-diol(3),dehydroabietic acid(4),7α-hydroxydehydroabietic acid(5),2β-hydroxypimaric acid(6),vanillin(7),catechin(8),p-hydroxybenzaldehyde(9),daucosterol(10).CONCLUSION All the compounds are isolated from the shells of this plant for the first time.

关 键 词：麒麟竭 果壳 化学成分 分离鉴定 

分 类 号：R284.1[医药卫生—中药学]