基于文本挖掘技术分析治疗精子活力低下症的中医用药规律  

Analysis of the Regularity of Traditional Chinese Medicine for Treating Low Sperm Motility Based on Text Mining Technology

作　　者：陈曙辉 林煦垚 张明强 陈立[2] 秦国政[3] CHEN Shu-hui;LIN Xu-yao;ZHANG Ming-qiang;CHEN Li;QIN Guo-zheng(School of Clinical Medicine,Yunnan University of Traditional Chinese Medicine,Kunming 650500,China;School of Computer,Wuhan University,Wuhan 430072,China;Yunnan Provincial Hospital of Traditional Chinese Medicine/The First Affiliated Hospital of Yunnan Universityof Traditional Chinese Medicine,Kunming 650021,China)

机构地区：[1]云南中医学院临床医学院,云南昆明650500 [2]武汉大学计算机学院,湖南武汉430072 [3]云南省中医医院/云南中医学院第一附属医院,云南昆明650021

出　　处：《云南中医中药杂志》2019年第1期19-22,共4页Yunnan Journal of Traditional Chinese Medicine and Materia Medica

基　　金：国家自然科学基金项目(81260540;81760872);国家中医药"十一五"重点学科中医男科学建设项目[国中医药发(2009)30号]

摘　　要：目的利用文本挖掘技术探索治疗精子活力低下症的常用中医用药规律,为临床治疗提供一定的参考依据。方法登录中国知网(CNKI)收集中医治疗精子活力低下症的相关文献,使用MySQL数据库,运用全文索引对数据进行归档存储,并人工降噪处理。利用数据挖掘中的关联规则算法,统计分析常用中药用药频率及药物协同关系规律,绘制协同药物网络图并进行分析讨论。结果中药协同关系分析显示菟丝子、枸杞子、淫羊藿、熟地黄、黄芪是治疗精子活力低下症最常用的中草药。结论常用中药用药规律,对临床应用具有一定指导意义,文本挖掘技术可以为中医药研究提供技术支持。Objective:To explore the regularity of traditional Chinese medicine for treating low sperm motility with text mining technology and provide a reference for clinical treatment.Methods:The relevant literature of TCM treatment of low sperm motility was collected by logging into China Knowledge Network(CNKI),and by using MySQL database and full-text index,data were archived and stored,with manual noise reduction.The association rule algorithm in data mining were used to make statistical analysis of commonly used drug frequency and drug synergistic relationship law and to draw a collaborative drug network map to analyze and discuss.Results:The synergistic relationship analysis of traditional Chinese medicine showed that Cuscuta chinensis,Lycium barbarum,Epimedium,Rehmannia glutinosa and Radix Astragali were the most commonly used Chinese herbal medicines for the treatment of low sperm motility.Conclusion:The commonly used medication rule of traditional Chinese medicine has certain guiding significance for clinical application.Text mining technology can provide technical support for Chinese medicine research.

关 键 词：精子活力低下症 中医 文本挖掘 用药规律 

分 类 号：R256.56[医药卫生—中医内科学]