膝关节骨性关节炎软骨损伤的MRI形态评分及T_2值变化与临床表现的相关性  

MRI morphological scores of cartilage injury in knee joint osteoarthritis and correlation between changes of T_2 value and clinical features

作　　者：董进[1] 韩瑞[1] 宋少辉[1] 龙斌[1] 张东友[1] Jin Dong;Rui Han;Shao-hui Song;Bin Long;Dong-you Zhang(Department of Radiology,Wuhan NO.1 Hospital,Wuhan,Hubei 430022,China)

机构地区：[1]武汉市第一医院放射科,湖北武汉430022

出　　处：《中国现代医学杂志》2019年第4期69-72,共4页China Journal of Modern Medicine

基　　金：湖北省武汉市卫计委科研项目(No:WX13C04)

摘　　要：目的探讨膝关节骨性关节炎(OA)软骨损伤MRI形态评分及T_2值变化与临床表现的相关性。方法选取2016年9月—2017年7月在武汉市第一医院诊治的膝关节OA患者72例作为研究组,选取同期该院健康体检者20例作为对照组,所有研究对象进行MRI检查。比较两组膝关节软骨不同区域T_2值,采用骨关节炎指数(WOMAC)和全器官磁共振评分(WORMS)分别评估两组研究者症状程度和MRI检查严重程度,分析T_2值与WOAMC、WORMS的相关性。结果研究组股骨外侧区(LF)、股骨内侧区(MF)、胫骨外侧区(LT)、胫骨内侧区(MT)及髌骨区(P)区域软骨T_2值高于对照组(P<0.05);Pearson相关分析结果表明,膝关节OA患者LF区域T_2值与WORMS评分无相关性(P>0.05);膝关节OA患者MF、LT、MT及P区域T_2值与WORMS评分均呈正相关(P<0.05);膝关节OA患者僵硬、疼痛、关节功能WOMAC评分及WOMAC总分与T_2值呈正相关(P <0.05)。结论 MRI检查T_2值与膝关节OA患者临床症状、软骨病变程度呈正相关,MRI检查能反映膝关节OA患者软骨损伤程度。Objective To investigate the relationship between MRI morphological scores,changes of MRI T2 value and clinical manifestations of cartilage injury in knee osteoarthritis(OA).Methods To select 72 cases of knee OA patients in our hospital from Sept.2016 to Jul.2017 as a research group and 20 volunteers in our hospital physical examination center health during the same period as a control group,and all subjects were examined by MRI.The T2 values of different regions of knee cartilage were compared between the two groups.The degree of symptoms and the severity showed by MRI were respectively evaluated by WOMAC and WORMS.The correlations between T2 value and WOAMC,WORMS were analyzed.Results The cartilage T2 values of LF,MF,LT,MT and P in the research group were significantly higher than those in the control group(P<0.05).Pearson analysis showed that there was no correlation between T2 value of LF and WORMS score in knee OA patients(r=0.011,P >0.05).There was a positive correlation between T2 value of MF,LT,MT,P and WORMS score(r=0.814,0.856,0.721,0.615,all P<0.05).Pearson analysis showed that stiffness,pain,WOMAC scores of joint function and total WOMAC score were positively correlated with T2 values(r=0.316,0.294,0.409 and 0.325,all P<0.05).Conclusions MRI T2 values and clinical symptoms of knee OA patients,degree of cartilage lesion were positively correlated.MRI can reflect the degree of cartilage injury in knee OA patients.

关 键 词：骨关节炎 膝 膝损伤 软骨 磁共振成像 体征和症状 

分 类 号：R445.2[医药卫生—影像医学与核医学]