超重和肥胖者左心室几何形变及同步性变化分析  

Left ventricular geometric deformation and synchronicity changes in overweight and obese population

作　　者：彭雪莲 梁杉 赵香芝 李明星 刘洁 Xue-lian Peng;Shan Liang;Xiang-zhi Zhao;Ming-xing Li;Jie Liu(Department of Ultrasonography,the Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan 646000,China)

机构地区：[1]西南医科大学附属医院超声科,四川泸州646000

出　　处：《中国现代医学杂志》2019年第4期78-82,共5页China Journal of Modern Medicine

摘　　要：目的应用实时三维超声心动图(RT-3DE)技术评价超重和肥胖者左心室球形指数及其收缩、舒张同步性变化,并分析其影响因素。方法选取西南医科大学附属医院健康管理中心的100例健康体检者,按体重指数(BMI)分为正常组、超重组及肥胖组。收集一般资料,相关实验室检查结果,采集左心室三维全容积动态图像,应用RT-3DE技术获得左心室球形指数及同步性相关参数。比较各组间左心室球形指数及同步性参数是否存在差异,分析左心室几何形变及同步性变化的影响因素。结果 3组收缩压、舒张压、胆固醇、三酰甘油及低密度脂蛋白比较,差异有统计学意义(P<0.05)。3组舒张末球形指数(EDSI)、收缩末球形指数(ESSI)、舒张期失同步指数(DDI)及收缩期失同步指数(SDI)的比较,差异有统计学意义(P <0.05)。左心室EDSI、ESSI、DDI及SDI与BMI呈正相关(P <0.05)。左心室EDSI、ESSI、DDI及SDI与腰围(WC)呈正相关(P <0.05)。多重线性回归分析发现,WC与左心室EDSI有相关性(P <0.05),BMI与左心室ESSI、DDI及SDI有相关性(P<0.05)。结论超重和肥胖者左心室几何形态趋于球形变化,左心室壁运动同步性减低;BMI、WC可能为超重、肥胖者左心室几何形变及同步性变化的影响因素。Objective To evaluate the changes of left ventricular spherical index and synchronicity in overweight and obese populations with real-time three-dimensional echocardiography,and to analysis the influence factors.Methods Totally 100 healthy people from the health management center of the affiliated hospital of southwest medical university were divided into three groups according to the BMI:the normal group(n=40),the overweight group(n=30)and the obese group(n=30).The general data,related laboratory test results and the three-dimensional dynamic images of left ventricular were collected in all the study participants,and the relevant parameters of left ventricular spherical index and synchronicity were obtained by RT-3DE technique.To compare the differences between left ventricular spherical index and synchronicity parameters in each group.The influence factors of left ventricular geometric deformation and synchronicity changes in overweight and obese were analyzed.Results There were significant differences in systolic blood pressure,diastolic blood pressure,cholesterol,triglyceride and low density lipoprotein among the three groups(P<0.05).There were significant differences in EDSI,ESSI,DDI and SDI among the three groups(P<0.05).Left ventricular EDSI,ESSI,DDI and SDI were positively correlated with BMI and WC respectively.Stepwise multiple linear regression revealed that WC was correlated with left ventricular EDSI and BMI was correlated with left ventricular ESSI,DDI and SDI.Conclusions Left ventricular geometric shape tends to sphere and left ventricular wall motion synchronicity decreases in overweight and obese people.BMI and WC may be influence factors of left ventricular geometric deformation and synchronicity changes in overweight and obese people.

关 键 词：超声心动描记术 人体质量指数 诊断试验 常规 

分 类 号：R589.2[医药卫生—内分泌]