某院麻醉药品和一类精神药品的处方分析  

Analysis on the narcotic drugs prescription and the first category of psychotropic drugs prescription for patients in hospital

作　　者：程小桂 王振兴[1] 邹绮雯 许夏燕[1] 曹伟灵[1] CHENG Xiao-gui;WANG Zhen-xing;ZOU Qi-wen;XU Xia-yan;CAO Wei-ling(Department of pharmacy of Luohu people hospital,shenzhen 518001,China)

机构地区：[1]深圳市罗湖区人民医院药学部,广东深圳518001

出　　处：《中国处方药》2019年第2期1-4,共4页Journal of China Prescription Drug

基　　金：广东省深圳市罗湖区软科学研究(2017035)

摘　　要：目的了解麻醉药品、一类精神药品的应用情况,为临床合理用药提供参考。方法选取2016年～2017年各药房的麻醉药品、一类精神药品账册、登记本和处方,采用WHO推荐的限定日剂量(DDD)为测定单位,计算各麻醉药品、一类精神药品的用药频率(DDDs)和药物利用指数(DUI),对患者的用药情况进行统计分析,了解合理用药情况。结果 2016年使用的麻、精一药品共14种,2017年减少为11种,处方数女性为男性的2倍,其中使用最广泛的三种麻醉药品是芬太尼注射液、舒芬太尼注射液和瑞芬太尼注射液;问题处方数从2016年的36.22%降为2017年的0.89%,但同时出现了右上角标识错误、无临床诊断、修改处未签名盖章等新问题。2016年DUI> 1的麻醉药品有芬太尼透皮贴、芬太尼注射液。2017年DUI> 1的麻醉药品有芬太尼透皮贴、芬太尼注射液、硫酸吗啡缓释片。结论麻醉药品、一类精神药品处方合格率仍没有达到100%,同时芬太尼透皮贴和硫酸吗啡缓释片皆因给药频率不规范导致DUI> 1,所以仍需进一步加强麻醉药品、一类精神药品使用指导原则相关知识的培训,使麻、精一药品的使用更安全、合理、规范。Objective To analyze the application of the narcotic drugs and the first category of psychotropic drugs in our hospital for the rational use of drugs.Methods The narcotic drugs prescriptions and the first category of psychotropic drugs prescriptions and the books recorded the drugs of each department of pharmacy were collected from 2016 to 2017,and recommended defined daily doses(DDD),defined daily doses system(DDDs)and drug use index(DUI),which was recommended by WHO to analyze the usage of drugs on patients.Results There were 14 kinds of narcotic drugs and the first category of psychotropic drugs in our hospital in 2016,and 11 kinds in 2017.There were twice as many prescriptions as men in the two years.The most widely used narcotic drugs and the first category of psychotropic drugs were fentanyl,sufentanil and remifentanil;The number of problem prescription decreased from 36.22%in 2016 to 0.89%in 2017,but there were new problems in the upper right corner,such as marked error,no clinical diagnosis,unsigned and sealed by the modification.Fentanyl transdermal patches,fentanyl injection(DUI >1)used unreasonable in 2016 and 2017,included morphine hydrochloride sustained-release tablets(DUI >1)in 2017.Conclusion The rate of prescription of narcotic drugs and the first category of psychotropic drugs in our hospital is still not 100%,at the same time,because of the irregular frequency of delivery of fentanyl transdermal patches and morphine hydrochloride sustained-release tablets result in DUI greater than 1.Therefore,it is necessary to further strengthen the training of knowledge related to the guiding principles for the use of narcotic drugs and the first category of psychotropic drugs,so as to make the use of the drugs in our hospital safer,more reasonable and more standardized.

关 键 词：麻醉药品 一类精神药品 处方分析 用药频率 药物利用指数 合理用药 

分 类 号：R95[医药卫生—药学]