消化道癌症患者家族癌症史发生情况分析  

Analysis of family cancer history in patients with digestive tract cancer

作　　者：刘娜[1] 胡一河 王临池[1] 黄春妍[1] 杨海兵[1] 陈立凌[1] LIU Na;HU Yihe;WANG Linchi;HUANG Chunyan;YANG Haibing;CHEN Liling(Suzhou Center for Disease Control and Prevention,Suzhou,Jiangsu 215004,China)

机构地区：[1]江苏省苏州市疾病预防控制中心,江苏苏州215004

出　　处：《公共卫生与预防医学》2019年第1期56-59,共4页Journal of Public Health and Preventive Medicine

基　　金：苏州市"科教兴卫"青年科技项目(kjxw2015037;kjxw2016046);江苏省卫生和计划生育委员会课题(Y2015019);苏州市科技局2015年度第九批产业技术创新专项(应用基础研究.医疗卫生)(SYS2015081);苏州市重大疾病;传染病预防和控制关键技术(GWZX201503);苏州市民生科技-关键技术研究(SS201545);苏州市医学重点学科(Szxk201516)

摘　　要：目的分析消化道癌症患者家族癌症史、家族消化道癌症史发生情况。方法采用面对面调查的方法依据《人群疾病家族史和病史调查表》对江苏省苏州市某6个乡镇的消化道癌症患者进行调查,内容包括:一般情况、一二三级亲属家系构成及其亲属患癌症情况。结果 720位消化道癌症患者中阳性家族癌症史、阳性消化道癌症家族史发生率分别为36.67%、28.61%;病例的家族癌症史及家族消化道癌症史的发生率性别差异无统计学意义(P均>0.05);病例家族患癌症和消化道癌症的成员人数多集中在3人及以下,患病成员越多的家族越少见(趋势χ~2检验P<0.05);一级亲属癌症史、消化道癌症史发生率分别为4.46%和3.37%,均明显高于二三级亲属(P均<0.05)。结论针对性地开展宣教活动,提高对消化道癌症高危家族的鉴别能力,进而对其进行重点健康教育工作,全面落实疾病三级预防网络,将对苏州市消化道癌症防控工作有极其重要意义。Objective To analyze the family cancer and digestive tract cancer history in patients with digestive tract cancer. Methods Patients with digestive tract cancer in some six townships in Suzhou city were investigated by means of face-to-face survey based on the "Family History and History of Population Diseases Questionnaire" which includes general conditions, the composition and cancer occurrence of all three degree relatives. Results The incidence of positive family cancer and digestive tract cancer history in 720 patients with digestive tract cancer was 36.67% and 28.61%, respectively. There is no gender difference in the incidence of family cancer and digestive tract cancer history with P both above 0.05;the number of members of these cases’ family suffering from cancer and digestive tract cancer is mostly concentrated in 3 people or less, and the more families with more members, the less common they are(Trend χ~2 test,P<0.05);the incidence of first-degree relatives’ cancer and digestive tract cancer history was 4.46% and 3.37%, respectively, which was significantly higher than the second-level and third-level relatives with P all below 0.05. Conclusion Carrying out some activities focusing on improving the ability to identify some high-risk families of digestive tract cancer, and conducting key health education work with fully implement the three-level disease prevention network will be extremely important

关 键 词：消化道癌症 家族癌症史 一级亲属 

分 类 号：R181[医药卫生—流行病学]