福州地区6606例儿童呼吸道感染病原体IgM抗体检测结果分析  

Analysis of IgM antibodies detection results of pathogens in 6 606 children with respiratory tract infection

作　　者：杨秀钦[1] 吴志辉[1] 倪琛[1] YANG Xiuqin;WU Zhihui;NI Chen(Department of clinical laboratory,Fujian Provincial Maternity and Children's Hospital,Fuzhou,Fujian 350001,China)

机构地区：[1]福建省妇幼保健院检验科,福州350001

出　　处：《福建医药杂志》2019年第1期16-18,共3页Fujian Medical Journal

摘　　要：目的分析福州地区患儿呼吸道系统疾病病原体分布情况及流行病学特点,为本地区儿童呼吸道感染的预防及诊治提供参考依据。方法选择我院2017年3月至2018年2月住院的儿科呼吸道感染患儿6 606例,应用间接免疫荧光法同时检测9种常见上呼吸道感染病原体的血清IgM抗体。结果检出呼吸道病原体IgM抗体阳性的2 333例(35.32%)。阳性率最高的3种病原体分别为肺炎支原体(MP,29.20%)、嗜肺军团菌(LP,4.37%)和流感病毒B型(FluB,3.22%)。9种病原体除肺炎衣原体外,其余8种的阳性率均存在季节性差异。病原体在各个年龄段分布比较的差异有统计学意义,以4～6岁组阳性率最高。结论初步了解掌握福州地区儿童呼吸道系统感染的流行病学特点和发病率,可为临床疾病诊疗提供参考。Objective To investigate the distribution of pathogens and epidemiological characteristics of children with respiratory tract infection in Fuzhou so as to provide reference for the prevention and treatment of children’s respiratory tract infection in this area.Methods Selected 6606 pediatric respiratory tract infections hospitalized children from March 2017 to February2018 in our hospital,and simultaneously tested the IgM antibody of nine common pathogens of upper respiratory tract infection by using indirect immunofluorescence assay(IFA).Results Among the 6606 samples,2333 were positive for respiratory pathogen IgM antibody,and the positive rate was 35.32%.The three pathogens with the highest positive rate were respectively Mycoplasma pneumonia 29.20%,Legionella pneumophila 4.37%,influenza B virus 3.22%.Except Chlamydia pneumoniae the positive rate of the nine pathogens showed seasonal difference.The distribution of pathogens in different age groups was statistically significant,and the positive rate was highest in the 4-6 age group.Conclusion The epidemiological characteristics and incidence of children’s respiratory tract infection in Fuzhou area can be preliminarily understood through detection and analysis,which can provide references for clinical diagnosis and treatment.

关 键 词：呼吸道感染 呼吸道病原体 儿童 

分 类 号：R725.6[医药卫生—儿科]