漳州地区930例过敏患者过敏原检测结果分析  

Analysis of allergen detection results of 930 allergic patients in Zhangzhou area

作　　者：陆璇 洪和泉 陈印春 李裕权 LU Xuan;HONG Hequan;CHEN Yinchun;LI Yuquan(Zhangzhou Skin Disease Prevention and Treatment Hospital,Zhangzhou,Fujian 363000,China)

机构地区：[1]福建省漳州市皮肤病防治院检验科,漳州363000

出　　处：《福建医药杂志》2019年第1期25-27,共3页Fujian Medical Journal

摘　　要：目的分析漳州地区皮肤过敏患者对食入性与吸入性过敏原的过敏情况以及过敏原在人群中的分布特征,作为过敏原地区流行病学的研究分析。方法选取2017年1月至12月漳州市皮肤病防治院门诊皮肤过敏患者930例,按患者性别及年龄大小进行分组,应用德国Mediwiss敏筛(Allergy Screen)过敏原免疫印迹定量检测系统对患者血清特异性过敏原sIgE进行检测。结果吸入性过敏原sIgE检出率较食入性过敏原sIgE高,检出阳性率分别为60.9%和29%,两组差异有统计学意义(P<0.05)。在吸入性过敏原sIgE中,以尘螨sIgE的检测阳性率最高,为46.56%;而在食入性过敏原sIgE中,虾sIgE检测阳性率最高,为15.48%。结论漳州地区吸入性过敏原检测阳性率高于食入性过敏原。该地区最常见的吸入性过敏原为户尘螨;最常见的食入性过敏原为虾,在儿童组鸡蛋白和牛奶为主要过敏原。Objective To analyze the allergic condition of food allergens and inhalation allergens in allergic patients,as well as the distribution characteristics of allergens in the population for the analysis of epidemiology in areas with allergens.Methods A total of 930 allergic outpatients were selected in Skin Disease Prevention and Treatment Hospital of Zhangzhou City from January 2017 to December 2017.Included patients were divided based on gender and age.The immunoblotting quantitative detection system for allergens,made by Allergy Screen of Mediwiss(Germany),was employed to detect total IgE in serum and specific sIgE of included patients.Results Detection rate of sIgE in inhalation allergens was higher than that in food allergens,with the detection rate of 60.9% and 29%,respectively.The difference between the two groups was statistically significant(P<0.05).Among sIgE in inhalation allergens,the positive rate of sIgE in dust mites was detected to be the highest,which was46.56%.Among sIgE in food allergens,the positive rate of sIgE in shrimp was the highest of reaching 15.48%.ConclusionThe positive rate of inhalation allergens is higher than that of food allergens in Zhangzhou area.The most common inhalation allergen and food allergen is dust mites and shrimp in this area,respectively.Milk and egg whites are the main food allergens for children.

关 键 词：过敏原 特异性过敏原抗体sIgE 过敏性疾病 Ⅰ型超敏反应 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]