宫颈癌患者调强适形放疗摆位重复性及误差情况  

Repeatability and set-up error of intensity modulated conformal radiotherapy for patients with cervical cancer

作　　者：苏毅德 周含 冯茜[2] 杨孝伟 SU Yide;ZHOU Han;FENG Qian;YANG Xiaowei(Department of Radiotherapy,Nanjing General Hospital of People's Liberation Army,Nanjing 210000,Jiangsu,China;Department of Obstetrics and Gynecology,The 454 Hospital of People's Liberation Army,Nanjing 210000,Jiangsu,China)

机构地区：[1]中国人民解放军南京总医院放疗科,南京210000 [2]中国人民解放军第四五四医院妇产科,南京210002

出　　处：《中国性科学》2019年第1期60-62,共3页Chinese Journal of Human Sexuality

基　　金：南京总医院立项课题项目(2017051)

摘　　要：目的探究降低宫颈癌患者调强适形放疗摆位误差与重复性的有效措施。方法选择2016年4月至2017年4月中国人民解放军南京总医院收治的宫颈癌患者70例,按照入院顺序分为对照组和观察组两组实施对比研究,每组35例。两组患者均接受调强适形放疗,对照组给予常规摆位,观察组在对照组基础上,联合给予真空垫固定摆位。观察两组患者的放疗不同轴向(x、y、z轴)误差情况、总不良反应发生率等实验数据。结果对两组患者不同放疗不同轴向(x、y、z轴)误差情况进行统计比较,可得观察组在各轴向上的误差均显著小于对照组,差异具有统计学意义(all P <0. 05)。观察组不良反应发生率为5. 71%,显著低于对照组的25. 71%,,差异具有统计学意义(P <0. 05)。结论对接受调强适形放疗的宫颈癌患者,在对其进行摆位的时候,联合应用真空垫固定摆位效果确切,可以更好地减少放疗不同轴向上的误差,提高放疗的精确度。Objective To explore the effective measures to reduce the setup error and repeatability of intensity modulated conformal radiotherapy for patients with cervical cancer.Methods 70 patients with cervical cancer in our hospital from April 2016 to April 2017 were selected and divided into control group and observation group,with 35 cases in each group.Both the two groups received intensity-modulated radiotherapy.The control group was given routine positioning,and the observation group was given vacuum pad to fix the position on the basic positioning of the control group.Different axial radiotherapy(x,y,z axis)error,total adverse reaction rate and other experimental data of the two groups were observed.Results The error of two groups with different radiotherapy and different axis(x,y,z axis)were statistically compared.And the error of each axis in observation group was significantly smaller than that of the control group,with statistically significant difference(all P<0.05).In terms of radiotherapy related adverse reactions,the total incidence of adverse reactions in observation group(5.71%)was significantly lower than that in control group(25.71%),with statistically significant difference(all P<0.05).Conclusions For cervical cancer patients undergoing intensity-modulated radiotherapy,the combination of vacuum pad fixation has a definite effect,which can reduce the error of radiotherapy in different axial directions and improve the accuracy of radiotherapy.

关 键 词：宫颈癌 调强适形放疗 放疗摆位 真空垫固定 重复性 误差 

分 类 号：R711[医药卫生—妇产科学]