弥散加权成像技术在孕中晚期胎儿脑积水中的诊断价值研究  

Diagnostic Value of Nuclear Magnetic Resonance Imaging Diffusion Weighted Imaging in Middle and Late Pregnancy Fetal Hydrocephalus

作　　者：朱大林[1] 冯帆[2] 吴菊[3] 马强华[1] 杨来虎[1] 宋庆梅[3] ZHU Da-lin;WU Ju;FENG Fan(Medical Imaging Center,Gansu ProvinceMaternal and Child Care Hospital,Lanzhou 730050,Gansu Province,China)

机构地区：[1]甘肃省妇幼保健院医学影像中心,甘肃兰州730050 [2]甘肃省妇幼保健院生殖医学中心,甘肃兰州730050 [3]甘肃省妇幼保健院产前诊断中心,甘肃兰州730050

出　　处：《中国CT和MRI杂志》2018年第11期14-17,共4页Chinese Journal of CT and MRI

基　　金：甘肃省科技厅自然科学基金资助项目(项目编号:1308RJZA244)

摘　　要：目的探讨核磁共振扩散加权成像技术(Diffusionweightedimaging,DWI)在孕中晚期胎儿脑积水中的诊断价值研究。方法回顾性收集孕中晚期15例胎儿脑积水和28例正常胎儿的影像资料及临床资料,均行DWI扫描,分别测量脑室周围额叶、颞叶、顶叶、枕叶白质、基底节区、丘脑、脑干的表观弥散系数(apparentdiffusioncoefficient,ADC)值,两组之间进行比较。结果脑积水组和正常对照组胎儿在孕周(P=0.965)和孕妇年龄(P=0.981)上无明显统计学差异。与对照组比较,脑积水胎儿额叶(P=0.034)、顶叶(P=0.021)ADC值增高,差异有统计学意义(P<0.05)。颞叶(P=0.300)、枕叶(P=0.667)、基底节(P=1.005)、丘脑(P=0.444)、脑干(P=0.609)的ADC值,差异均无统计学意义。结论核磁共振DWI技术可以提高胎儿脑积水的诊断率,对产前诊断工作有重要的价值和指导意义。Objective To investigate the diagnostic value of diffusion weighted imaging(DWI)in fetal hydrocephalus in middle and late pregnancy.Methods Objective To analyze the imaging data and clinical data of 15 cases of hydrocephalus and 28 cases of normal fetus,and to measure the frontal lobe,temporal lobe,parietal lobe,occipital lobe,thalamus,basal Section of the brain,the brain stem of the ADC value,the hydrocephalus and normal fetal measurement results were analyzed.Results The hydrocephalus group and the normal control group fetus in gestational age(P=0.965)and pregnant women age(P=0.981)no significant difference.Compared with the control group,the hydrocephalus fetus frontal lobe(P=0.034),parietal lobe(P=0.021)ADC value increased statistically significant(P<0.05).ADC values of temporal lobe(P=0.300),occipital lobe(P=0.667),basal ganglia(P=1.005),thalamus(P=0.444)and brainstem(P=0.609)were not statistically different.Conclusion DWI sequence improve the diagnostic rate of fetal hydrocephalus,prenatal diagnosis has important value and guiding significance.

关 键 词：核磁共振 扩散加权成像 胎儿脑积水 

分 类 号：R714.5[医药卫生—妇产科学] R445.2[医药卫生—临床医学]