3.0T MRI在多发性肌炎和皮肌炎诊断中的价值研究  

Study on the Value of 3.0T MRI in the Diagnosis of Polymyositis and Dermatomyositis

作　　者：赵蕾[1] ZHAO Lei(Department of Dermatology,Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)

机构地区：[1]郑州大学第一附属医院皮肤科,河南郑州450052

出　　处：《中国CT和MRI杂志》2019年第2期146-148,共3页Chinese Journal of CT and MRI

摘　　要：目的探讨3.0TMRI在多发性肌炎(PM)和皮肌炎(DM)诊断中的价值。方法回顾性分析2015年1月至2017年7月我院收治的17例PM患者和22例DM患者临床资料,所有患者均进行3.0T MRI检查,分析其图像,并将其结果与血清肌酶各指标检查结果和肌肉活检结果进行比较。结果共39例PM和DM患者中,36例出现肌肉炎性水肿,11例表现为肌筋膜增厚(肌筋膜炎),18例出现皮下软组织水肿,8例出现肌肉萎缩伴脂肪浸润。肌筋膜炎、皮下软组织水肿者均出现肌肉炎性水肿。肌肉炎性水肿病变区T1WI呈等信号,T2WI呈高信号,STIR呈高信号;肌筋膜炎T1WI呈等信号,T2WI肌间隙呈高信号,STIR肌间隙呈高信号;皮下软组织水肿T1WI上皮下脂肪呈低信号,T2WI呈稍高信号,STIR呈高信号;肌肉萎缩伴脂肪浸润病变区T1WI呈短信号,T2WI呈长信号。3.0TMRI扫描结果与血清肌酶各指标检查结果相比,差异具有统计学意义(P<0.05)。3.0TMRI扫描结果与肌肉活检结果相比,差异无统计学意义(P>0.05)。结论 3.0TMRI在PM和DM诊断中具有重要应用价值,肌肉炎性水肿是PM和DM患者在3.0TMRI检查中最常见表现。Objective To explore the value of 3.0 T MRI in the diagnosis of polymyositis(PM)and dermatomyositis(DM).Methods The clinical data of 17 PM cases and 22 DM cases admitted to our hospital from January 2015 to July 2017 were analyzed retrospectively.All patients were given 3.0 T MRI examination,and their images were analyzed,and the results were compared with results of serum muscle enzymes markers and muscle biopsy.Results Among 39 PM and DM patients,there were 36 cases of muscular inflammatory edema,11 cases of myofascial thickening(myofascitis),18 cases of subcutaneous soft tissue edema and 8 cases of muscular atrophy and fat infiltration.Patients with myofasciitis and subcutaneous soft tissue edema tended to have muscular inflammatory edema.In inflammatory edema area of muscle,there was equal signal on T1 WI,high signal on T2 WI and high signal on STIR.In the intermuscular space of myofascialitis,there was equal signal on T1 WI,high signal on T2 WI and high signal on STIR.In the subepithelial fat of subcutaneous soft tissue edema,there was low signal on T1 WI showed,slightly high signal on T2 WI and high signal on STIR.In the area of muscle atrophy and fatty infiltration,there was short signal on T1 WI and long signal on T2 WI.There were significant differences between the results of 3.0 T MRI scan and the results of serum muscle enzymes markers(P<0.05).There was no significant difference between the 3.0 T MRI scan results and muscle biopsy results(P >0.05).Conclusion 3.0 T MRI has important application value in the diagnosis of PM and DM.Muscular edema is the most common manifestation of 3.0 T MRI in PM and DM patients.

关 键 词：3.0T MRI 多发性肌炎 皮肌炎 诊断价值 

分 类 号：R44[医药卫生—诊断学] R74[医药卫生—临床医学]