MRI及功能成像改变对新生儿高胆红素脑病临床价值分析  

Clinical Value of MRI and Functional Imaging in Newborn Bilirubin Encephalopathy

作　　者：靳金岩 李洪义 JIN Jin-yan;LI Hong-yi(Department of Radiology,Mudanjiang City Women andChildren Hospital,Mu Danjiang 157000,Heilongjiang Province,China)

机构地区：[1]牡丹江市妇女儿童医院放射线科,黑龙江牡丹江157000 [2]牡丹江医学院附属红旗医院磁共振科,黑龙江牡丹江157000

出　　处：《中国CT和MRI杂志》2019年第1期12-14,24,共4页Chinese Journal of CT and MRI

摘　　要：目的探究新生儿高胆红素脑病患儿MRI及功能成像的影像表现,及MRI对新生儿高胆红素脑病的临床诊断、鉴别诊断价值。方法回顾性分析临床综合为新生儿高胆红素脑病的患儿共68例,根据血清总胆红素水平分3组,均行MR平扫、DWI及MRS扫描,观察不同MR系列上影像表现及MRS各物质峰值变化,并分析以上指标与NBE诊断的相关性。结果 68例患儿T1WI、T2WI及T2压水序列均可检出NBE,其中T1WI序列较其他序列具有更高的灵敏性;3组患儿两侧大脑半球病灶T1WI信号强度差异均无统计学意义,而组间T1WI信号强度差异有统计学意义;T1WI高信号病灶在MRS上表现为NAA/Cr降低,Cho/Cr、Cho/NAA增高,其MRS表现与T1WI等信号病灶比较,差异具有统计学意义。结论MRI及功能成像可用于NBE的诊断,值得临床推广。Objective To investigate the imaging findings,diagnostic value of MRI and functional imaging in children with newborn bilirubin encephalopathy(NBE).Methods A total of 68 cases of NBE which diagnosed by clinical were analyzed retrospectively.All cases accepted MR plain scan,DWI and MRS scan and were divided into three groups according to the serum total bilirubin level.Analyze the imaging features of different MR sequences,the changes of the peak values of various substances on MRS images and the correlation with the NBE.Results Both of T1WI,T2WI and T2 water pressure sequences could be used to diagnosed NBE,and T1WI was more sensitive than the others;there was no significant difference in the bilateral T1WI signal intensity in 3 groups of children while there was significant difference among the three groups,and the T1WI high signal lesions showed the decrease of NAA/Cr and the increase of Cho/Cr,Cho/NAA in MRS.The MRS findings of T1WI high signal lesions were significantly different from those of T1WI equal signal lesions.Conclusion MRI and functional imaging could be used to the diagnosis of NBE and was worthy of clinical promotion.

关 键 词：新生儿高胆红素脑病 MRI 功能成像 MRS 临床价值 

分 类 号：R722.1[医药卫生—儿科]