肾功能衰竭合并脑出血应用无肝素序贯血液透析治疗的临床可行性分析  

Clinical Feasibility Analysis of Heparin-free Hemodialysis in Patients with Renal Failure Complicated with Cerebral Hemorrhage

作　　者：田宇[1] TIAN Yu(Department of Nephrology, 313 Hospital of Chinese People's Liberation Army, Huludao 125000, China)

机构地区：[1]葫芦岛市解放军313医院肾内科,辽宁葫芦岛125000

出　　处：《中国医药指南》2019年第4期10-11,共2页Guide of China Medicine

摘　　要：目的探究对肾功能衰竭合并脑出血患者应用无肝素序贯血液透析能够取得的治疗效果。方法将58例我院于2015年10月至2017年9月收治的肾功能衰竭合并脑出血患者作为实验对象。结果观察组治疗有效率显著高于对照组,治疗7 d与治疗14 d后观察组的MMP-9/IL-8/IL-10水平以及血肿、水肿大小明显优于对照组,数据差异均有统计学意义(P<0.05)。结论无肝素血液透析治疗对于肾功能衰竭合并脑出血能够取得良好的治疗效果,其中无肝素序贯血液透析能够明显缓解患者的病情,改善治疗效果。与单纯无肝素血液透析相比能够有效改善患者预后,具有临床推广应用价值。Objective To explore the therapeutic effect of heparin-free sequential hemodialysis in patients with renal failure complicated with intracerebral hemorrhage. Methods 58 patients with renal failure complicated with intracerebral hemorrhage admitted in our hospital from October 2015 to September 2017 were selected as experimental subjects. Results The effective rate of treatment in the observation group was significantly higher than that in the control group. The levels of MMP-9/IL-8/IL-10 and hematoma in the observation group were significantly higher than those in the control group 7 days after treatment and 14 days after treatment. The size of edema was better than that of control group, and the difference was statistically significant (P <0.05). Conclusion Non-heparin hemodialysis is effective in the treatment of renal failure complicated with intracerebral hemorrhage. Good therapeutic effect can be achieved, in which no heparin sequential hemodialysis can significantly alleviate the patient's condition and improve the therapeutic effect. Compared with heparin-free hemodialysis alone, it can effectively improve the prognosis of patients.

关 键 词：肾功能衰竭 脑出血 无肝素血液透析 序贯透析 

分 类 号：R692.5[医药卫生—泌尿科学] R743.34[医药卫生—外科学]