黄芪多糖对猪瘟疫苗免疫效果影响的Meta分析  

Meta-analysis on the Effect of Astragalus Polysaccharide on the Immune Effect of Swine Fever Vaccine

作　　者：朱道仙[1] 陆江[1] 卢炜[1] 傅宏庆[1] Zhu Daoxian;Lu Jiang;Lu Wei(Jiangsu Agriculture and Animal Husbandry Vocational College of Science and Technology, Jiangsu Taizhou 225300,China)

机构地区：[1]江苏农牧科技职业学院,江苏泰州225300

出　　处：《四川畜牧兽医》2019年第2期25-27,30,共4页Sichuan Animal & Veterinary Sciences

基　　金：江苏高校品牌专业建设工程资助项目(PPZY2015C230)

摘　　要：为了系统评价黄芪多糖对猪瘟疫苗免疫效果的影响,通过检索数据库资料,纳入有关黄芪多糖对猪瘟疫苗免疫效果影响的随机对照试验(共纳入11个对照试验,样本量为244头猪),利用Cochrane Reviewer′s Handbook 5.0评价标准对试验质量进行评价,并使用Revman 5.3进行统计分析。结果显示:黄芪多糖可显著提高血液中的猪瘟抗体水平,同时提高其血液中的IL-2含量,优于单纯免疫组。表明黄芪多糖可通过提高机体的体液免疫和细胞因子水平来增强猪瘟疫苗的免疫效果,效果确切,值得推广应用。In order to systematically evaluate the effect of Astragalus polysaccharide on the immune effect of classical swine fever(SFV) vaccine, randomized controlled trials on the effect of Astragalus polysaccharide on the immune effect of CSF vaccine were included by searching the database data(a total of 11 controlled trials were included, with a sample size of 244 pigs). The Cochrane Reviewer′s Handbook 5.0 evaluation standard was used to evaluate its quality, and Revman 5.3 was used for statistical analysis. The results showed that Astragalus polysaccharide can significantly increase the antibody level of CSF in the blood and increase the IL-2 content in the blood, which were superior to the pure immunization group. The results indicated that Astragalus polysaccharide can enhance the immune effect of CSF vaccine by improving the levels of humoral immunity and cytokine, its effect is exact, can be promoted and applied.

关 键 词：黄芪多糖 猪瘟疫苗 猪瘟抗体 白介素-2 META分析 

分 类 号：S818.9[农业科学—畜牧学]