射干抗病毒口服液和射干抗病毒注射液抗炎作用的比较分析  

Comparative study on the anti-inflammatory effects between shegan antiviral oral liquid and injection

作　　者：贾佳[1] 张平[1] 王银娟[1] 苏华[1] JIA Jia;ZHANG Ping;WANG Yinjuan;SU Hua(Department of Production Section,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu 210002,China)

机构地区：[1]中国人民解放军南京军区南京总医院制剂科,江苏南京210002

出　　处：《安徽医药》2019年第3期463-465,共3页Anhui Medical and Pharmaceutical Journal

基　　金：军队医疗机构制剂标准提高科研专项课题(13ZJZ15-2)

摘　　要：目的比较射干抗病毒口服液和射干抗病毒注射液的抗炎作用。方法通过二甲苯致小鼠耳廓肿胀实验观察射干抗病毒口服液及射干抗病毒注射液的抗炎作用。结果口服液的高剂量组与注射液的中、高剂量组都可明显抑制二甲苯所致小鼠耳肿胀度(与空白组比较,P<0.05,其中口服液高剂量组P=0.006、注射液中剂量组P=0.004、注射液高剂量组P=0.010)。但射干抗病毒口服液和射干抗病毒注射液的抗炎作用差异无统计学意义(P>0.05)。结论射干抗病毒口服液及射干抗病毒注射液均具有明显的抗炎作用,且口服液与注射液的抗炎作用差异不明显。Objective To compare the anti-inflammatory effects between Shegan Antiviral Oral Liquid and Shegan Antiviral Injection.Methods The anti-inflammatory effects of Shegan Antiviral Oral Liquid and Shegan Antiviral Injection were studied in swelling ears of mice induced by xylene.Results High dose of Oral liquid,medium and high doses of Injection could restrain mice swelling ears caused by xylene(compared with the blank group,P<0.05.High dose of Oral liquid:P=0.006,medium doses of Injection:P=0.004,high doses of Injection:P=0.010).However,there was no significant difference between Shegan Antiviral Oral Liquid and Shegan Antiviral Injection in anti-inflammatory test(P>0.05).Conclusion Shegan Antiviral Oral Liquid and Shegan Antiviral Injection have significant anti-inflammatory effects,while with no significant difference between them.

关 键 词：射干抗病毒注射液 射干抗病毒口服液 抗炎 药效学 

分 类 号：R285.5[医药卫生—中药学]