成人腰椎软骨终板的组织学特征  

Histological properties of adult lumbar cartilage endplate

作　　者：孙毅[1] 梁彦超[2] 武峰[1] 蒋安龙 闫景龙[1] SUN Yi;LIANG Yan-chao;WU Feng;JIANG An-long;YAN Jing-long(Department of Orthopaedics,2nd Affiliated Hospital of Harbin Medical University,Harbin 150010,Heilongjiang,China;Department of Orthopaedics,4th Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang,China)

机构地区：[1]哈尔滨医科大学附属第二医院骨科,哈尔滨150010 [2]哈尔滨医科大学附属第四医院骨科,哈尔滨150001

出　　处：《脊柱外科杂志》2019年第1期47-50,共4页Journal of Spinal Surgery

摘　　要：目的探讨健康成人腰椎软骨终板组织学特征。方法选取18具新鲜成人尸体腰椎标本,死亡原因为车祸伤或意外,无腰椎外伤和糖尿病。从8个不同区域取材,制备软骨终板样本,利用高敏感测高仪测量软骨终板厚度,通过显微镜观察经HE染色后终板的组织学特征。结果不同区域软骨终板厚度差异有统计学意义(P <0.05),终板厚度为0.696～1.045 mm,后区下部终板最厚,中央区上部最薄。HE染色结果显示,软骨终板的细胞密度比髓核和纤维环的细胞密度高,软骨终板中央区和侧区的胶原纤维分别比髓核和纤维环组织中的胶原纤维更加紧密。结论腰椎不同区域软骨终板厚度不同,其组织学特征与椎间盘的营养供应相关。Objective To study the histological properties of the healthy adult lumbar vertebral cartilage endplate.Methods Eighteen fresh adult cadaveric lumbar spine specimens were selected.The causes of death were traffic accidents or accidents,no lumbar spine injury or diabetes mellitus.Cartilage endplate samples were prepared from 8 different regions.The thickness of the cartilage endplate was measured by a highly sensitive altimeter.The histological characteristics of the endplate were observed under microscope after HE staining.Results The difference in thickness of the cartilage endplate in different regions was statistically significant(P<0.05).The thickness range of the endplate was 0.696-1.045 mm,the thickest was at the lower part in the posterior region,and the thinnest at the upper part in the central region.HE staining showed that the cell density of the cartilage endplate was much higher than that of the nucleus pulposus or annulus fibrosus.The collagen fibers in the cartilage endplate from central and lateral regions were more compact than those in the nucleus pulposus and annulus fibrosus tissues,respectively.Conclusion The thickness of the cartilage endplate is different in different regions of the lumbar spine,and its histological features are related to the nutritional supply of the intervertebral disc.

关 键 词：腰椎 椎间盘退行性变 组织学 

分 类 号：R681.533[医药卫生—骨科学]