高频短时无肝素血液透析治疗尿毒症合并脑出血的临床效果观察  

Clinical observation of high frequency short time heparin free hemodialysis in the treatment of uremia complicatedwith cerebral hemorrhage

作　　者：田宇[1] TIAN Yu(Department of Nephrology, 313 Hospital of Chinese People's Liberation Army, Huludao, 125000, China)

机构地区：[1]葫芦岛市解放军313医院肾内科,辽宁葫芦岛125000

出　　处：《中国医药指南》2019年第5期8-9,共2页Guide of China Medicine

摘　　要：目的探究对尿毒症合并脑出血患者应用高频短时无肝素血液透析治疗能够取得的疗效。方法将48例我院于2016年8月至2017年7月收治的尿毒症合并脑出血患者作为研究对象,随机分为高频组和常规组,每组24例。高频组行高频短时无肝素血液透析治疗,常规组行常规无肝素血液透析治疗。观察两组的治疗效果。结果治疗后7 d、14 d高频组患者的MMP-9、IL-8、IL-10水平优于常规组,血肿和水肿的大小小于常规组,且并发症发生率低于常规组,数据差异均有统计学意义(P <0.05)。结论高频短时无肝素血液透析对于尿毒症合并脑出血患者能够取得良好的疗效,在改善治疗效果的同时,能够降低并发症的发生,值得临床推广应用。Objective To explore the effect of high frequency short time heparin free hemodialysis on uremic patients with cerebral hemorrhage.Methods 48 cases of uremia with cerebral hemorrhage were treated in our hospital from August 2016 to July 2017. The patients were randomlydivided into high frequency group and routine group, with 24 patients in each group. High frequency group was treated with high frequencyhemodialysis without heparin, and routine group without routine heparin hemodialysis. The therapeutic effects of the two groups were observed.Results After treatment, the level of MMP-9, IL-8, IL-10 in 7 d and 14 d high frequency group was better than that of the conventional group. Thesize of hematoma and edema was less than that of the conventional group, and the incidence of complications was lower than that of the conventionalgroup, and the difference of data was statistically significant(P<0.05). Conclusion High frequency and short time heparin free hemodialysis canachieve good curative effect in patients with uremia and cerebral hemorrhage. It can reduce the occurrence of complications while improving thetherapeutic effect. It is worthy of clinical application.

关 键 词：尿毒症 脑出血 高频短时 无肝素血液透析 

分 类 号：R692.5[医药卫生—泌尿科学] R743.34[医药卫生—外科学]