米粒状氧化铜化学修饰电极的制备及其对葡萄糖的检测  

Rice-like CuO Chemically Modified Electrode: Preparation and Detection for Glucose

作　　者：邓敏[1] 江奇[1] 段志虹 刘青青[1] 蒋理[1] 卢晓英[1] DENG Min;JIANG Qi;DUAN Zhi-Hong;LIU Qing-Qing;JIANG Li;LU Xiao-Ying(Key Laboratory of Advanced Technologies of Materials(Ministry of Education of China),School of Life Science and Engineering,School of Electrical Engineering,Southwest Jiaotong University,Chengdu 610031,China)

机构地区：[1]西南交通大学超导与新能源研发中心生命科学与工程学院材料先进技术教育部重点实验室,成都610031

出　　处：《无机材料学报》2019年第2期152-158,共7页Journal of Inorganic Materials

基　　金：国家自然科学基金(50907056;51602266);四川省重点研发计划(2017GZ0109);四川省科技支撑项目(2016GZ0273;2016GZ0275);四川省学术与技术带头人培养基金~~

摘　　要：采用水热合成法与原位分解法相结合,在不使用软模板和强碱条件下制备得到了米粒状氧化铜(CuO)。将得到的CuO材料与Nafion溶液混合,制作成化学修饰电极(CME),开展葡萄糖的无酶检测。采用X射线衍射仪(XRD)和扫描电子显微镜(SEM)分别对所制备的材料和电极的结构、形貌进行表征、分析。采用线性扫描伏安法、循环伏安法、安培响应和交流阻抗技术对所制备电极进行电化学性能测试。研究结果表明:所制备的CuO形貌在微观下酷似米粒,长度为0.5～1.0μm,直径为250～320 nm。当CuO修饰量为0.35 mg (电极表面积为0.22 cm2)时,修饰电极对葡萄糖具有较好的电化学检测性能。在0.0357～2.361 mmol/L浓度范围内存在良好的线性关系,其线性方程为:Ipa(mA)=?0.00187+0.05239c (mmol/L), R2=0.998。检出限为0.0647μmol/L,灵敏度为950.36μA·L/(mmol·cm2),且具有良好的选择性和可靠性。A novel rice-like copper oxide(CuO)was synthesized without using soft template and alkali by hydrothermal and in-situ decomposition methods.This rice-like CuO material was made into the chemically modified electrode(CME)with Nafion solution for non-enzymatic glucose sensing.Structure and morphology of the prepared material and electrode were characterized by X-ray diffraction and scanning electron microscopy.Electrochemical performances of the obtained electrodes were investigated by linear sweep voltammetry,cyclic voltammetry,amperometric response,and electrochemical impedance spectroscopy.Results show that morphology of the obtained CuO particle is similar to rice grain.And its length and diameter are between 0.5?1.0μm and 250?320 nm,respectively.The CME with 0.35 mg rice-like CuO(with 0.22 cm2 electrode surface area)has an obvious current response for glucose with the linear range from 0.0357 to 2.361 mmol/L,the linear equation Ipa(mA)=-0.00187+0.05239 c(mmol/L)(R2=0.998),the detection limit 0.0647μmol/L,and the sensitivity 950.36μA·L/(mmol·cm2).Therefore,the prepared CuO CME shows a promise selectivity and reliability for detecting glucose.

关 键 词：米粒状CuO 化学修饰电极 葡萄糖 检测 

分 类 号：O657[理学—分析化学]