超声引导下经支气管针吸活检在肺结节病早期诊断中的价值  

Value of endobronchial ultrasound-guided tranbronchial needle aspiration in early diagnosis of patients with pulmonary sarcoidosis

作　　者：赵海军 林浩然 王静[3] 孙培莉[4] ZHAO Haijun;LIN Haoran;WANG Jing;SUN Peili(Department of Pulmonary Disease,Guanyun County Hospital of Traditional Chinese Medicine,Lianyungang, Jiangsu,222200;Department of Thoracic Surgery The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,210029;Department of Endocrinology The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,210029;Department of Respiratory,The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,210029)

机构地区：[1]江苏省灌云县中医院肺病科,江苏连云港222200 [2]南京医科大学第一附属医院胸外科,江苏南京210029 [3]南京医科大学第一附属医院内分泌科,江苏南京210029 [4]南京医科大学第一附属医院呼吸内科,江苏南京210029

出　　处：《实用临床医药杂志》2019年第4期5-8,共4页Journal of Clinical Medicine in Practice

摘　　要：目的探讨超声引导下经支气管针吸活检(EBUS-TBNA)在肺结节病中的诊断价值。方法回顾性分析130例肺结节病患者的临床表现、实验室及影像学检查等资料。结果本研究肺结节病患者中,Ⅰ期101例,Ⅱ期28例,Ⅲ期1例。临床表现主要为呼吸系统症状,影像学可表现为肺门及纵隔淋巴结肿大、肺内及胸膜病变等。本研究患者均进行淋巴结活检,其中应用EBUS-TBNA明确诊断者119例(91. 5%)。结论肺结节病临床表现无特异性,影像学发现双侧肺门及纵隔淋巴结肿大者应怀疑为此病。EBUS-TBNA具有创伤小、对Ⅰ及Ⅱ期结节病诊断率高特点,在肺结节病的诊断中具有重要价值。Objective To investigate the value of endobronchial ultrasound-guided tranbronchial needle aspiration(EBUS-TBNA)in early diagnosis of patients with pulmonary sarcoidosis.Methods The clinical manifestations,laboratory examinations and imaging results of 130 patients with pulmonary sarcoidosis were retrospectively reviewed.Results In patients with pulmonary sarcoidosis,there were 101 cases with stageⅠ,28 cases with stageⅡand 1 case with stageⅢ.The main clinical manifestations were respiratory symptoms,and imaging findings included hilar and mediastinal lymph node enlargement,intrapulmonary and pleural lesions.Lymph node biopsy was performed in all patients in this study,among which 119 cases(91.5%)were definitely diagnosed by EBUS-TBNA.Conclusion The clinical manifestations of pulmonary sarcoidosis are not specific.If bilateral hilar and mediastinal lymphadenopathy are found by imaging,pulmonary sarcoidosis should be suspected.EBUS-TBNA has the characteristics of minimal trauma and high diagnostic rate for stageⅠandⅡsarcoidosis,which is of great value in the diagnosis of pulmonary sarcoidosis.

关 键 词：肺结节病 临床特征 超声引导下经支气管针吸活检 影像学 

分 类 号：R563.9[医药卫生—呼吸系统]