重症甲状腺功能亢进-心力衰竭-严重肝功能损伤一例并文献复习  

Severe Hyperthyroidism-Heart Failure-Severe Liver Injury:Report of One Case and Literature Review

作　　者：廉慧 阳洪波[2] 郭潇潇[3] 袁涛[2] 柴晓峰[2] 邢小平[2] 连小兰[2] LIAN Hui;YANG Hongbo;GUO Xiaoxiao;YUAN Tao;CHAI Xiaofeng;XING Xiaoping;LIAN Xiaolan(Healthcare Department,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Department of Endocrinology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Department of Cardiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院保健医疗部,北京100730 [2]中国医学科学院北京协和医学院北京协和医院内分泌科,北京100730 [3]中国医学科学院北京协和医学院北京协和医院心内科,北京100730

出　　处：《中国医学科学院学报》2019年第1期134-138,共5页Acta Academiae Medicinae Sinicae

摘　　要：重症甲状腺功能亢进可造成心、肝等多个器官损伤,并可危及生命。北京协和医院收治了1名青年女性,因未规律服用抗甲状腺药物出现重症甲状腺功能亢进,表现为甲状腺功能亢进性心脏病、严重的肝功能损伤。收住院后使用抗甲状腺药物治疗原发病,并积极纠正心力衰竭、控制心房颤动。病程中患者出现胆红素重度升高,给予激素及保肝治疗后症状改善。定期随访,临床表现良好。Severe hyperthyroidism can cause the injuries of multiple organs including heart and liver and ultimately be fatal.A 26-year-old young woman admitted to Peking Union Medical College Hospital for severe hyperthyroidism due to irregular use of anti-thyroid drugs.She had heart failure,atrial fibrillation,and severe liver damage at admission.Anti-thyroid drugs were then actively used to treat the primary disease,along with interventions to correct heart failure and control atrial fibrillation.Severe total bilirubin elevation was found during the treatment,which was resolved after the use of glucocorticoid and liver-protective therapy.The patient was regularly followed up after discharge,and the clinical manifestations were good.

关 键 词：重症甲状腺功能亢进 心力衰竭 心房颤动 黄疸 

分 类 号：R581[医药卫生—内分泌]