吡嗪酰腙配体Cu(Ⅱ)/Ni(Ⅱ)配合物的合成、晶体结构及DNA结合性质（英文）  

Syntheses, Crystal Structures and DNA-Binding Properties of Cu(Ⅱ)/Ni(Ⅱ) Complexes with Acylhydrazone Ligand Bearing Pyrazine Unit

作　　者：王碗碗 王元 张玲 宋雨飞 吴伟娜 陈忠 WANG Wan-Wan;WANG Yuan;ZHANG Ling;SONG Yu-Fei;WU Wei-Na;CHEN Zhong(College of Chemistry and Chemical Engineering, Henan Key Laboratory of Coal Green Conversion,Henan Polytechnic University, Jiaozuo, Henan 454000, China;School of Materials and Mechanical and Electrical Engineering, Jiangxi Science andTechnology Normal University, Nanchang 330013, China)

机构地区：[1]河南理工大学化学化工学院河南省煤炭绿色转化重点实验室,焦作454000 [2]江西科技师范大学材料与机电学院,南昌330013

出　　处：《无机化学学报》2019年第3期563-568,共6页Chinese Journal of Inorganic Chemistry

基　　金：国家自然科学基金(No.21001040);河南省自然科学基金(No.182300410183,162300410011);江西省自然科学基金(No.20181BAB206011);河南省教育厅高等学校重点科研基金(No.19A150001);江西省教育厅科学技术研究项目(No.GJJ170665);河南理工大学校内基金(No.T2018-3,J2015-4);江西科技师范大学校内基金(No.2015QNBJRC006)资助

摘　　要：合成并通过单晶衍射、元素分析及红外光谱表征了配合物[Ni(L)(HL)](SO_4)_(0.5)·3CH_3OH (1)和[Cu_2(L)_2SO_4]·1.5CH_3OH (2)的结构(HL为3-甲基-2-乙酰吡嗪苯甲酰腙)。单晶衍射实验结果表明,在配合物1中,Ni(Ⅱ)中心离子与2个酰肼配体的[ONN]配位原子组配位,形成扭曲的八面体配位构型;2的最小非对称单元中含有1个独立的双核Cu(Ⅱ)配合物分子,它的2个Cu(Ⅱ)中心由2个酰肼配体中的2个O原子桥联。每个Cu(Ⅱ)离子还与L-配体中的2个氮原子和η_2-SO_4^(2-)阴离子中的1个O原子配位,拥有扭曲的四方锥配位构型。此外,荧光光谱表明配合物和DNA的结合能力强于配体。Two complexes, namely [Ni(L)(HL)](SO4)0.5·3CH3OH (1) and [Cu2(L)2SO4]·1.5CH3OH (2)(HL=3-methyl- 2-acetylpyrazine benzoylhydrazone) have been synthesized and characterized by single crystal X-ray diffraction, elemental analysis and IR spectroscopy. X-ray diffraction analysis results showed that in complex 1, the center Ni (Ⅱ)ion with a distorted octahedron geometry is surrounded by two acylhydrazones with [ONN] donor set. However, complex 2 contains one discrete dimeric Cu(Ⅱ)molecule in the unit cell, in which two Cu(Ⅱ)ions were doubly bridged by two O atoms from two independent acylhydrazone ligands. Each of the Cu(Ⅱ)ions is also coordinated by two N atoms from one L- ligand and one O atom from the η2-SO4 2- anion, thus giving a distorted square pyramid coordination geometry. Moreover, the fluorescence spectra indicated that the interaction of the complexes to DNA is stronger than that of the ligand HL. CCDC 1876785: 1;1876789: 2.

关 键 词：酰肼 Cu(Ⅱ)配合物 DNA结合 Ni(Ⅱ)配合物 吡嗪 

分 类 号：O614.121[理学—无机化学] O614.813[理学—化学]