生物3D打印——从形似到神似  

3D bioprinting: from structure to function

作　　者：贺永[1] 高庆[1] 刘安[1] 孙苗[1] 傅建中[1] HE Yong;GAO Qing;LIU An;SUN Miao;FU Jian-zhong(State Key Laboratory of Fluid Power and Mechatronic Systems,School of Mechanical Engineering,Zhejiang University,Hangzhou 310027,China)

机构地区：[1]浙江大学流体动力与机电系统国家重点实验室机械工程学院,浙江杭州310027

出　　处：《浙江大学学报（工学版）》2019年第3期407-419,共13页Journal of Zhejiang University：Engineering Science

基　　金：国家自然科学基金优秀青年科学基金资助项目(51622510);浙江省杰出青年科学基金资助项目(LR17E050001)

摘　　要：系统回顾生物3D打印的提出背景,给出生物3D打印的研究范围,梳理生物3D打印的发展历程.重点聚焦于回顾操纵细胞的生物3D打印研究,并结合课题组近年来的研究及思考,对生物3D打印的发展进行展望.更好地结合临床需求,实现从组织结构的仿生制造过渡到功能化的再造是生物3D打印未来取得突破的关键.Review the background of 3D bioprinting systematically,provide the research scope of 3D bioprinting,and summarize the development of 3D bioprinting.This review focuses on the 3D bioprinting of manipulating cells,and the development of 3D bioprinting was prospected combined with the research and thought of our research group in recent years.To better integrate clinical needs to realize transition from bionic manufacturing of organizational structure to functional reconstruction is the key to the breakthrough of 3D bioprinting in the future.

关 键 词：生物3D打印 细胞打印 生物墨水 生物打印机 组织工程 仿生制造 

分 类 号：R318.08[医药卫生—生物医学工程]