创伤前口服阿司匹林对创伤性颅脑损伤术后患者预后的影响  

Impact of prognosis in preinjury aspirin treatment patients with traumatic brain injury after operation

作　　者：张业森[1] 苏贺先[1] Zhang Yesen;Su Hexian(Department of Neurosurgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu 233004)

机构地区：[1]蚌埠医学院第一附属医院,安徽蚌埠233004

出　　处：《中国现代医药杂志》2019年第2期27-30,共4页Modern Medicine Journal of China

摘　　要：目的探讨创伤前口服阿司匹林对创伤性颅脑损伤(TBI)患者临床预后的影响。方法采用格拉斯哥昏迷评分法(GCS)评定颅脑损伤患者入院时神经恶化情况,术后24h复查头颅CT对患者术后情况进行评定,出院时格拉斯哥预后量表(GOS)对患者进行功能评定,出院后6个月随访并采用生活自理能力评分(ADL),对患者生活自理能力进行评价。结果阿司匹林组与非用药组入院时GCS评分、术后再出血、出院时GOS评分、预后良好率和随访ADL评分及生活自理率无统计学差异(P>0.05),但阿司匹林组住院期间死亡率较非用药组高(P<0.05)。结论术前口服阿司匹林不能引起神经损害加重及增加残疾率,未影响患者出院总体预后,但可能会增加患者住院期间死亡率。Objective To investigate the effect of preoperative aspirin treatment on the prognosis of patients with traumatic brain injury(TBI)after operation.Methods The Glasgow coma score was used to assess the neurological deterioration of the patients with craniocerebral injury at admission.24 hours after the operation,the craniocerebral CT was evaluated after the operation,and the Glasgow prognosis scale(GOS)was used to assess the patients'outcome,the patients were followed up for 6 months after discharge,and the patients were evaluated with self-care ability score(ADL).Results There was no significant difference in GCS score,postoperative hemorrhage,prognosis of GOS score and ADL score between the aspirin group and non-aspirin group(P>0.05),but the mortality rate of aspirin group was higher than that of non-aspirin group(P<0.05).Conclusion Preoperative aspirin treatment does not cause aggravation of nerve damage,and does not increase the rate of disability.It does not affect the overall prognosis of discharged patients,but may increase the mortality during hospitalization.

关 键 词：创伤性颅脑损伤 阿司匹林 预后 

分 类 号：R651.15[医药卫生—外科学]