糖尿病合并Dieulafoy病患者临床特征分析  

Analysis of Clinical Features of Patients with Diabetes Complicated with Dieulafoy Disease

作　　者：宋进展 徐光耀[1] 周海燕 李晶晶 SONG Jin-zhan;XU Guang-yao;ZHOU Hai-yan;LI Jing-jing(Department of Endocrinology,Yanqing District Hospital,Beijing 3rd Hospital of Peking University,Yanqing Hospital,Beijing,102100 China;Department of Gastrointestinal,Yanqing District Hospital,Beijing,Beijing University Third Hospital Yanqing Hospital,Beijing,102100 China)

机构地区：[1]北京市延庆区医院(北京大学第三医院延庆医院)内分泌科,北京102100 [2]北京市延庆区医院(北京大学第三医院延庆医院)胃镜室,北京102100

出　　处：《糖尿病新世界》2019年第2期44-46,共3页Diabetes New World Magazine

摘　　要：目的探讨糖尿病合并Dieulafoy病患者的临床特征。方法对北京大学第三医院延庆医院胃镜室2009年10月—2018年6月确诊的24例Dieulafoy病的临床资料进行回顾性分析调查,根据是否合并糖尿病,分为糖尿病组与非糖尿病组,对比两组相关临床特征的差别。结果糖尿病组平均年龄(62.00±14.06)岁,胃肠道伴随症状12.50%(1/8),溃疡平均直径(0.40±0.11)cm,1周内再次出血几率25.00%(2/8),与非糖尿病组的(44.69±10.86)岁,56.25%(9/16),(0.25±0.13)cm,0.00%(0/16)比较差异有统计学意义(t=3.517、χ2=4.025、t=2.200、χ2=4.128,P<0.05)。另外两组在口服阿司匹林诱因及合并高血压、心血管疾病构成上差异有统计学意义(χ2=9.043、9.375、9.000,P<0.05)。糖尿病组溃疡部位分布构成及病死率与非糖尿病组比较差异无统计学意义(χ2=0.321、0.000,P>0.05)。结论糖尿病合并Dieulafoy病患者平均年龄偏大,合并高血压、心血管疾病多,多有口服阿司匹林诱因,胃肠道伴随症状不明显,溃疡偏大,再次出血几率高。Objective To investigate the clinical features of patients with diabetes complicated with Dieulafoy disease.Methods The clinical data of 24 cases of Dieulafoy's disease diagnosed in the gastroscope of Yanqing Hospital of Peking University Third Hospital were retrospectively analyzed from October 2009 to June 2018.According to whether or not diabetes was divided into diabetes group and non-diabetes group,the clinical characteristics of the two groups were compared.Results The mean age of the diabetic group was(62.00±14.06)years old,the gastrointestinal symptoms were 12.50%(1/8),the average diameter of the ulcer was(0.40±0.11)cm,and the probability of recurrence within 1 week was 25.00%(2/8).In the non-diabetic group(44.69±10.86)years old,56.25%(9/16),(0.25±0.13)cm,0.00%(0/16),the difference was statistically significant(t=3.517,χ^2=4.025,t= 2.200,χ^2= 4.128,P<0.05).There were also statistically significant differences between the two groups in the induction of oral aspirin and the combination of hypertension and cardiovascular disease(χ^2=9.043,9.375,9.000,P<0.05).There was no significant difference in the distribution and mortality of the ulcer site between the diabetic group and the non-diabetic group(χ^2= 0.321,0.000,P>0.05).Conclusion The average age of patients with diabetes complicated with Dieulafoy disease is large,with hypertension and cardiovascular disease.Most of them have induced aspirin,gastrointestinal symptoms are not obvious,the ulcer is too large,and the chance of re-bleeding is high.

关 键 词：糖尿病 DIEULAFOY病 临床特征 

分 类 号：R587.2[医药卫生—内分泌]