红景天提取物对高原缺氧条件下肉鸡法氏囊疫苗免疫作用的影响  

Effect of Rhodiola Extracts on Antibody Responses to Vaccinate Bursal Disease Virus in Broiler Chickens Reared at High-altitude Hypoxia Condition

作　　者：李龙 仇薪鑫 刘锁珠 闫红军[1] LI Long;QIU Xin-xin;LIU Suo-zhu;YAN Hong-jun(Department of Animal Engineering,Yangling Vocational and Technical College,Yangling 712100,China;Animal Science College,Tibet Agriculture and Animal Husbandry College,Linzhi 860000,China)

机构地区：[1]杨凌职业技术学院动物工程分院,陕西杨凌712100 [2]西藏农牧学院动物科学学院,西藏林芝860000

出　　处：《畜牧与饲料科学》2019年第2期9-11,共3页Animal Husbandry and Feed Science

基　　金：国家自然科学基金项目(31560651);陕西省教育厅专项研究计划(17JK0881)

摘　　要：试验旨在研究红景天提取物对高原缺氧条件下肉鸡接种法氏囊疫苗和绵羊红细胞后产生的特异性抗体水平的影响。随机选取100只1日龄健康AA肉仔鸡,随机分为5组。其中,对照组只饲喂基础日粮,其余4组分别在基础日粮中添加0.10%、0.15%、0.20%和0.40%红景天水提物干粉。每个组取半数鸡只于13日龄腹腔注射接种绵羊红细胞,另一半鸡只于20日龄口服接种法氏囊疫苗。研究发现,免疫接种法氏囊疫苗后2 d和19 d,相比于对照组,0.20%和0.40%红景天处理组显著提高了法氏囊疫苗抗体水平(P<0.05)。在腹腔注射绵羊红细胞后5 d、8 d和12 d时,相比对照组,0.20%和0.40%红景天处理组显著提高了绵羊红细胞抗体水平(P<0.05)。该试验表明红景天提取物可以提高高海拔缺氧条件下肉鸡特异性抗体水平,因此其可能作为高海拔缺氧条件下肉鸡日粮的一种免疫调节性添加剂。In this study, we tested whether Rhodiola extracts had any effects on antibody responses to infectious bursal disease virus (IBDV)and sheep red blood cells (SRBC)in broiler chickens reared high-altitude hypoxia condition. A total of 100 1-day-old healthy AA broilers were randomly divided into 5 treatments. Four treatments received dietary supplementation of 0.10%, 0.15%, 0.20%and 0.40%dry powder of Rhodiola aqueous extracts in basal diet, respectively, and the other group serving as control fed basal diet without supplementation. Half of the broilers in each treatment were injected intraperitoneally 1 mL of a 10% suspension of SRBC at 13 d of age, and the others were orally vaccinated at 20 d of age with the Bursine-2 live virus. The results showed that compared to the control group, supplementation of 0.20%and 0.40% Rhodiola extracts significantly increased the IBDV antibody titer at 2 d and 19 d after vaccination (P<0.05), and increased the SRBC antibody titer at 5 d, 8 d and 12 d after inoculation (P<0.05). In conclusion, dietary supplementation with Rhodiola extracts could increase the specific antibody level in broiler chickens reared at high-altitude hypoxia condition. Therefore, Rhodiola extracts may be act as an immune regulator additive for broilers reared high-altitude hypoxia condition.

关 键 词：红景天提取物 缺氧 肉鸡 抗体 

分 类 号：S831.5[农业科学—畜牧学]